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An oligoclonal antibody durably overcomes resistance of lung cancer to third-generation EGFR inhibitors.
Mancini M, Gal H, Gaborit N, Mazzeo L, Romaniello D, Salame TM, Lindzen M, Mahlknecht G, Enuka Y, Burton DG, Roth L, Noronha A, Marrocco I, Adreka D, Altstadter RE, Bousquet E, Downward J, Maraver A, Krizhanovsky V, Yarden Y. Mancini M, et al. Among authors: burton dg. EMBO Mol Med. 2018 Feb;10(2):294-308. doi: 10.15252/emmm.201708076. EMBO Mol Med. 2018. PMID: 29212784 Free PMC article.
Senescent cells communicate via intercellular protein transfer.
Biran A, Perelmutter M, Gal H, Burton DG, Ovadya Y, Vadai E, Geiger T, Krizhanovsky V. Biran A, et al. Among authors: burton dg. Genes Dev. 2015 Apr 15;29(8):791-802. doi: 10.1101/gad.259341.115. Epub 2015 Apr 8. Genes Dev. 2015. PMID: 25854920 Free PMC article.
NKG2D ligands mediate immunosurveillance of senescent cells.
Sagiv A, Burton DG, Moshayev Z, Vadai E, Wensveen F, Ben-Dor S, Golani O, Polic B, Krizhanovsky V. Sagiv A, et al. Among authors: burton dg. Aging (Albany NY). 2016 Feb;8(2):328-44. doi: 10.18632/aging.100897. Aging (Albany NY). 2016. PMID: 26878797 Free PMC article.
MTH1 counteracts oncogenic oxidative stress.
Burton DG, Rai P. Burton DG, et al. Oncoscience. 2015 Sep 12;2(10):785-6. doi: 10.18632/oncoscience.240. eCollection 2015. Oncoscience. 2015. PMID: 26682244 Free PMC article. No abstract available.
MutT Homolog 1 (MTH1) maintains multiple KRAS-driven pro-malignant pathways.
Patel A, Burton DG, Halvorsen K, Balkan W, Reiner T, Perez-Stable C, Cohen A, Munoz A, Giribaldi MG, Singh S, Robbins DJ, Nguyen DM, Rai P. Patel A, et al. Among authors: burton dg. Oncogene. 2015 May 14;34(20):2586-96. doi: 10.1038/onc.2014.195. Epub 2014 Jul 14. Oncogene. 2015. PMID: 25023700 Free PMC article.
18 results