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Page 1
Safety, tolerability, and immunogenicity of two Zika virus DNA vaccine candidates in healthy adults: randomised, open-label, phase 1 clinical trials.
Gaudinski MR, Houser KV, Morabito KM, Hu Z, Yamshchikov G, Rothwell RS, Berkowitz N, Mendoza F, Saunders JG, Novik L, Hendel CS, Holman LA, Gordon IJ, Cox JH, Edupuganti S, McArthur MA, Rouphael NG, Lyke KE, Cummings GE, Sitar S, Bailer RT, Foreman BM, Burgomaster K, Pelc RS, Gordon DN, DeMaso CR, Dowd KA, Laurencot C, Schwartz RM, Mascola JR, Graham BS, Pierson TC, Ledgerwood JE, Chen GL; VRC 319; VRC 320 study teams. Gaudinski MR, et al. Among authors: burgomaster k. Lancet. 2018 Feb 10;391(10120):552-562. doi: 10.1016/S0140-6736(17)33105-7. Epub 2017 Dec 5. Lancet. 2018. PMID: 29217376 Free PMC article. Clinical Trial.
DNA vaccination before conception protects Zika virus-exposed pregnant macaques against prolonged viremia and improves fetal outcomes.
Van Rompay KKA, Keesler RI, Ardeshir A, Watanabe J, Usachenko J, Singapuri A, Cruzen C, Bliss-Moreau E, Murphy AM, Yee JL, Webster H, Dennis M, Singh T, Heimsath H, Lemos D, Stuart J, Morabito KM, Foreman BM, Burgomaster KE, Noe AT, Dowd KA, Ball E, Woolard K, Presicce P, Kallapur SG, Permar SR, Foulds KE, Coffey LL, Pierson TC, Graham BS. Van Rompay KKA, et al. Among authors: burgomaster ke. Sci Transl Med. 2019 Dec 18;11(523):eaay2736. doi: 10.1126/scitranslmed.aay2736. Sci Transl Med. 2019. PMID: 31852797 Free PMC article.
Distinct neutralizing antibody correlates of protection among related Zika virus vaccines identify a role for antibody quality.
Maciejewski S, Ruckwardt TJ, Morabito KM, Foreman BM, Burgomaster KE, Gordon DN, Pelc RS, DeMaso CR, Ko SY, Fisher BE, Yang ES, Nair D, Foulds KE, Todd JP, Kong WP, Roy V, Aleshnick M, Speer SD, Bourne N, Barrett AD, Nason MC, Roederer M, Gaudinski MR, Chen GL, Dowd KA, Ledgerwood JE, Alter G, Mascola JR, Graham BS, Pierson TC. Maciejewski S, et al. Among authors: burgomaster ke. Sci Transl Med. 2020 Jun 10;12(547):eaaw9066. doi: 10.1126/scitranslmed.aaw9066. Sci Transl Med. 2020. PMID: 32522807
Development of a potent Zika virus vaccine using self-amplifying messenger RNA.
Luisi K, Morabito KM, Burgomaster KE, Sharma M, Kong WP, Foreman BM, Patel S, Fisher B, Aleshnick MA, Laliberte J, Wallace M, Ruckwardt TJ, Gordon DN, Linton C, Ruggiero N, Cohen JL, Johnson R, Aggarwal K, Ko SY, Yang ES, Pelc RS, Dowd KA, O'Hagan D, Ulmer J, Mossman S, Sambor A, Lepine E, Mascola JR, Pierson TC, Graham BS, Yu D. Luisi K, et al. Among authors: burgomaster ke. Sci Adv. 2020 Aug 7;6(32):eaba5068. doi: 10.1126/sciadv.aba5068. eCollection 2020 Aug. Sci Adv. 2020. PMID: 32821824 Free PMC article.
Functional Profiling of Antibody Immune Repertoires in Convalescent Zika Virus Disease Patients.
Fahad AS, Timm MR, Madan B, Burgomaster KE, Dowd KA, Normandin E, Gutiérrez-González MF, Pennington JM, De Souza MO, Henry AR, Laboune F, Wang L, Ambrozak DR, Gordon IJ, Douek DC, Ledgerwood JE, Graham BS, Castilho LR, Pierson TC, Mascola JR, DeKosky BJ. Fahad AS, et al. Among authors: burgomaster ke. Front Immunol. 2021 Feb 24;12:615102. doi: 10.3389/fimmu.2021.615102. eCollection 2021. Front Immunol. 2021. PMID: 33732238 Free PMC article.
Broadly neutralizing monoclonal antibodies protect against multiple tick-borne flaviviruses.
VanBlargan LA, Errico JM, Kafai NM, Burgomaster KE, Jethva PN, Broeckel RM, Meade-White K, Nelson CA, Himansu S, Wang D, Handley SA, Gross ML, Best SM, Pierson TC, Fremont DH, Diamond MS. VanBlargan LA, et al. Among authors: burgomaster ke. J Exp Med. 2021 May 3;218(5):e20210174. doi: 10.1084/jem.20210174. J Exp Med. 2021. PMID: 33831142 Free PMC article.
Limited Flavivirus Cross-Reactive Antibody Responses Elicited by a Zika Virus Deoxyribonucleic Acid Vaccine Candidate in Humans.
Burgomaster KE, Foreman BM, Aleshnick MA, Larman BC, Gordon DN, Maciejewski S, Morabito KM, Ledgerwood JE, Gaudinski MR, Chen GL, Mascola JR, Debbink K, Dowd KA, Graham BS, Pierson TC. Burgomaster KE, et al. J Infect Dis. 2021 Nov 16;224(9):1550-1555. doi: 10.1093/infdis/jiab185. J Infect Dis. 2021. PMID: 33961055 Free PMC article.
30 results