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Inactivation of the riboswitch-controlled GMP synthase GuaA in Clostridioides difficile is associated with severe growth defects and poor infectivity in a mouse model of infection.
Smith-Peter E, Séguin DL, St-Pierre É, Sekulovic O, Jeanneau S, Tremblay-Tétreault C, Lamontagne AM, Jacques PÉ, Lafontaine DA, Fortier LC. Smith-Peter E, et al. Among authors: lamontagne am. RNA Biol. 2021 Nov 12;18(sup2):699-710. doi: 10.1080/15476286.2021.1978768. Epub 2021 Oct 6. RNA Biol. 2021. PMID: 34612173 Free PMC article.
Monitoring RNA dynamics in native transcriptional complexes.
Chauvier A, St-Pierre P, Nadon JF, Hien EDM, Pérez-González C, Eschbach SH, Lamontagne AM, Penedo JC, Lafontaine DA. Chauvier A, et al. Among authors: lamontagne am. Proc Natl Acad Sci U S A. 2021 Nov 9;118(45):e2106564118. doi: 10.1073/pnas.2106564118. Proc Natl Acad Sci U S A. 2021. PMID: 34740970 Free PMC article.
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