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Desacetyl-α-melanocyte stimulating hormone and α-melanocyte stimulating hormone are required to regulate energy balance.
Mountjoy KG, Caron A, Hubbard K, Shome A, Grey AC, Sun B, Bould S, Middleditch M, Pontré B, McGregor A, Harris PWR, Kowalczyk R, Brimble MA, Botha R, Tan KML, Piper SJ, Buchanan C, Lee S, Coll AP, Elmquist JK. Mountjoy KG, et al. Among authors: coll ap. Mol Metab. 2018 Mar;9:207-216. doi: 10.1016/j.molmet.2017.11.008. Epub 2017 Nov 24. Mol Metab. 2018. PMID: 29226825 Free PMC article.
Peripheral administration of the N-terminal pro-opiomelanocortin fragment 1-28 to Pomc-/- mice reduces food intake and weight but does not affect adrenal growth or corticosterone production.
Coll AP, Fassnacht M, Klammer S, Hahner S, Schulte DM, Piper S, Tung YC, Challis BG, Weinstein Y, Allolio B, O'Rahilly S, Beuschlein F. Coll AP, et al. J Endocrinol. 2006 Aug;190(2):515-25. doi: 10.1677/joe.1.06749. J Endocrinol. 2006. PMID: 16899584 Free PMC article.
Orexin expression is regulated by alpha-melanocyte-stimulating hormone.
López M, Lage R, Tung YC, Challis BG, Varela L, Virtue S, O'Rahilly S, Vidal-Puig A, Diéguez C, Coll AP. López M, et al. Among authors: coll ap. J Neuroendocrinol. 2007 Sep;19(9):703-7. doi: 10.1111/j.1365-2826.2007.01577.x. J Neuroendocrinol. 2007. PMID: 17680885 Free PMC article.
FTO is necessary for the induction of leptin resistance by high-fat feeding.
Tung YC, Gulati P, Liu CH, Rimmington D, Dennis R, Ma M, Saudek V, O'Rahilly S, Coll AP, Yeo GS. Tung YC, et al. Among authors: coll ap. Mol Metab. 2015 Feb 7;4(4):287-98. doi: 10.1016/j.molmet.2015.01.011. eCollection 2015 Apr. Mol Metab. 2015. PMID: 25830092 Free PMC article.
Heterogeneity of hypothalamic pro-opiomelanocortin-expressing neurons revealed by single-cell RNA sequencing.
Lam BYH, Cimino I, Polex-Wolf J, Nicole Kohnke S, Rimmington D, Iyemere V, Heeley N, Cossetti C, Schulte R, Saraiva LR, Logan DW, Blouet C, O'Rahilly S, Coll AP, Yeo GSH. Lam BYH, et al. Among authors: coll ap. Mol Metab. 2017 Mar 1;6(5):383-392. doi: 10.1016/j.molmet.2017.02.007. eCollection 2017 May. Mol Metab. 2017. PMID: 28462073 Free PMC article.
91 results