Kopajtic T - Search Results

1

Structure-Activity Relationship Studies on a Series of 3α-[Bis(4-fluorophenyl)methoxy]tropanes and 3α-[Bis(4-fluorophenyl)methylamino]tropanes As Novel Atypical Dopamine Transporter (DAT) Inhibitors for the Treatment of Cocaine Use Disorders.

Zou MF, Cao J, Abramyan AM, Kopajtic T, Zanettini C, Guthrie DA, Rais R, Slusher BS, Shi L, Loland CJ, Newman AH. Zou MF, et al. Among authors: kopajtic t. J Med Chem. 2017 Dec 28;60(24):10172-10187. doi: 10.1021/acs.jmedchem.7b01454. Epub 2017 Dec 11. J Med Chem. 2017. PMID: 29227643 Free PMC article.

2

Secondary amine analogues of 3 beta-(4'-substituted phenyl)tropane-2 beta-carboxylic acid esters and N-norcocaine exhibit enhanced affinity for serotonin and norepinephrine transporters.

Boja JW, Kuhar MJ, Kopajtic T, Yang E, Abraham P, Lewin AH, Carroll FI. Boja JW, et al. Among authors: kopajtic t. J Med Chem. 1994 Apr 15;37(8):1220-3. doi: 10.1021/jm00034a021. J Med Chem. 1994. PMID: 8164265

3

Halogenated mazindol analogs as potential inhibitors of the cocaine binding site at the dopamine transporter.

Houlihan WJ, Boja JW, Parrino VA, Kopajtic TA, Kuhar MJ. Houlihan WJ, et al. Among authors: kopajtic ta. J Med Chem. 1996 Dec 6;39(25):4935-41. doi: 10.1021/jm960288w. J Med Chem. 1996. PMID: 8960553

4

N-substituted phenyltropanes as in vivo binding ligands for rapid imaging studies of the dopamine transporter.

Scheffel U, Lever JR, Abraham P, Parham KR, Mathews WB, Kopajtic T, Carroll FI, Kuhar MJ. Scheffel U, et al. Among authors: kopajtic t. Synapse. 1997 Apr;25(4):345-9. doi: 10.1002/(SICI)1098-2396(199704)25:4<345::AID-SYN5>3.0.CO;2-A. Synapse. 1997. PMID: 9097393

5

Dopamine transporter: transmembrane phenylalanine mutations can selectively influence dopamine uptake and cocaine analog recognition.

Lin Z, Wang W, Kopajtic T, Revay RS, Uhl GR. Lin Z, et al. Among authors: kopajtic t. Mol Pharmacol. 1999 Aug;56(2):434-47. doi: 10.1124/mol.56.2.434. Mol Pharmacol. 1999. PMID: 10419565

6

Structure-activity relationships at the monoamine transporters and sigma receptors for a novel series of 9-[3-(cis-3, 5-dimethyl-1-piperazinyl)propyl]carbazole (rimcazole) analogues.

Husbands SM, Izenwasser S, Kopajtic T, Bowen WD, Vilner BJ, Katz JL, Newman AH. Husbands SM, et al. Among authors: kopajtic t. J Med Chem. 1999 Oct 21;42(21):4446-55. doi: 10.1021/jm9902943. J Med Chem. 1999. PMID: 10543888

7

Highly selective chiral N-substituted 3alpha-[bis(4'-fluorophenyl)methoxy]tropane analogues for the dopamine transporter: synthesis and comparative molecular field analysis.

Robarge MJ, Agoston GE, Izenwasser S, Kopajtic T, George C, Katz JL, Newman AH. Robarge MJ, et al. Among authors: kopajtic t. J Med Chem. 2000 Mar 23;43(6):1085-93. doi: 10.1021/jm990265s. J Med Chem. 2000. PMID: 10737741

8

2D QSAR modeling and preliminary database searching for dopamine transporter inhibitors using genetic algorithm variable selection of Molconn Z descriptors.

Hoffman BT, Kopajtic T, Katz JL, Newman AH. Hoffman BT, et al. Among authors: kopajtic t. J Med Chem. 2000 Nov 2;43(22):4151-9. doi: 10.1021/jm990472s. J Med Chem. 2000. PMID: 11063611

9

Structure-activity relationships at monoamine transporters and muscarinic receptors for N-substituted-3alpha-(3'-chloro-, 4'-chloro-, and 4',4''-dichloro-substituted-diphenyl)methoxytropanes.

Newman AH, Robarge MJ, Howard IM, Wittkopp SL, George C, Kopajtic T, Izenwasser S, Katz JL. Newman AH, et al. Among authors: kopajtic t. J Med Chem. 2001 Feb 15;44(4):633-40. doi: 10.1021/jm000417f. J Med Chem. 2001. PMID: 11170654

10

Dopamine transporter binding without cocaine-like behavioral effects: synthesis and evaluation of benztropine analogs alone and in combination with cocaine in rodents.

Katz JL, Agoston GE, Alling KL, Kline RH, Forster MJ, Woolverton WL, Kopajtic TA, Newman AH. Katz JL, et al. Among authors: kopajtic ta. Psychopharmacology (Berl). 2001 Apr;154(4):362-74. doi: 10.1007/s002130000667. Psychopharmacology (Berl). 2001. PMID: 11349389

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