McClean MN - Search Results

1

Single-cell RNA sequencing reveals intrinsic and extrinsic regulatory heterogeneity in yeast responding to stress.

Gasch AP, Yu FB, Hose J, Escalante LE, Place M, Bacher R, Kanbar J, Ciobanu D, Sandor L, Grigoriev IV, Kendziorski C, Quake SR, McClean MN. Gasch AP, et al. Among authors: mcclean mn. PLoS Biol. 2017 Dec 14;15(12):e2004050. doi: 10.1371/journal.pbio.2004050. eCollection 2017 Dec. PLoS Biol. 2017. PMID: 29240790 Free PMC article.

2

Modeling single-cell phenotypes links yeast stress acclimation to transcriptional repression and pre-stress cellular states.

Bergen AC, Kocik RA, Hose J, McClean MN, Gasch AP. Bergen AC, et al. Among authors: mcclean mn. Elife. 2022 Nov 9;11:e82017. doi: 10.7554/eLife.82017. Elife. 2022. PMID: 36350693 Free PMC article.

3

The Yeast Optogenetic Toolkit (yOTK) for Spatiotemporal Control of Gene Expression in Budding Yeast.

Harmer ZP, McClean MN. Harmer ZP, et al. Among authors: mcclean mn. Methods Mol Biol. 2025;2840:19-36. doi: 10.1007/978-1-0716-4047-0_2. Methods Mol Biol. 2025. PMID: 39724341

4

Design and Implementation of an Automated Illuminating, Culturing, and Sampling System for Microbial Optogenetic Applications.

Stewart CJ, McClean MN. Stewart CJ, et al. Among authors: mcclean mn. J Vis Exp. 2017 Feb 19;(120):54894. doi: 10.3791/54894. J Vis Exp. 2017. PMID: 28287505 Free PMC article.

5

A yeast optogenetic toolkit (yOTK) for gene expression control in Saccharomyces cerevisiae.

An-Adirekkun JM, Stewart CJ, Geller SH, Patel MT, Melendez J, Oakes BL, Noyes MB, McClean MN. An-Adirekkun JM, et al. Among authors: mcclean mn. Biotechnol Bioeng. 2020 Mar;117(3):886-893. doi: 10.1002/bit.27234. Epub 2019 Dec 18. Biotechnol Bioeng. 2020. PMID: 31788779 Free PMC article.

6

Robust network structure of the Sln1-Ypd1-Ssk1 three-component phospho-relay prevents unintended activation of the HOG MAPK pathway in Saccharomyces cerevisiae.

Dexter JP, Xu P, Gunawardena J, McClean MN. Dexter JP, et al. Among authors: mcclean mn. BMC Syst Biol. 2015 Mar 25;9:17. doi: 10.1186/s12918-015-0158-y. BMC Syst Biol. 2015. PMID: 25888817 Free PMC article.

7

Engineered bacteria self-organize to sense pressure.

Morales NM, McClean MN. Morales NM, et al. Among authors: mcclean mn. Nat Biotechnol. 2017 Nov;35(11):1045-1047. doi: 10.1038/nbt.3992. Epub 2017 Oct 9. Nat Biotechnol. 2017. PMID: 28991269 No abstract available.

8

Cellular context alters EGF-induced ERK dynamics and reveals potential crosstalk with GDF-15.

Krause HB, Karls AL, McClean MN, Kreeger PK. Krause HB, et al. Among authors: mcclean mn. Biomicrofluidics. 2022 Oct 7;16(5):054104. doi: 10.1063/5.0114334. eCollection 2022 Sep. Biomicrofluidics. 2022. PMID: 36217350 Free PMC article.

9

Live-cell analysis of IMPDH protein levels during yeast colony growth provides insights into the regulation of GTP synthesis.

Shand EL, Sweeney K, Sundling KE, McClean MN, Brow DA. Shand EL, et al. Among authors: mcclean mn. mBio. 2024 Aug 14;15(8):e0102124. doi: 10.1128/mbio.01021-24. Epub 2024 Jun 28. mBio. 2024. PMID: 38940616 Free PMC article.

10

Lustro: High-Throughput Optogenetic Experiments Enabled by Automation and a Yeast Optogenetic Toolkit.

Harmer ZP, McClean MN. Harmer ZP, et al. Among authors: mcclean mn. ACS Synth Biol. 2023 Jul 21;12(7):1943-1951. doi: 10.1021/acssynbio.3c00215. Epub 2023 Jul 11. ACS Synth Biol. 2023. PMID: 37434272 Free PMC article.

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