Zheng Y - Search Results

1

Population Modeling of Tumor Kinetics and Overall Survival to Identify Prognostic and Predictive Biomarkers of Efficacy for Durvalumab in Patients With Urothelial Carcinoma.

Zheng Y, Narwal R, Jin C, Baverel PG, Jin X, Gupta A, Ben Y, Wang B, Mukhopadhyay P, Higgs BW, Roskos L. Zheng Y, et al. Clin Pharmacol Ther. 2018 Apr;103(4):643-652. doi: 10.1002/cpt.986. Epub 2018 Jan 17. Clin Pharmacol Ther. 2018. PMID: 29243222 Free PMC article.

2

Population Pharmacokinetics of Durvalumab in Cancer Patients and Association With Longitudinal Biomarkers of Disease Status.

Baverel PG, Dubois VFS, Jin CY, Zheng Y, Song X, Jin X, Mukhopadhyay P, Gupta A, Dennis PA, Ben Y, Vicini P, Roskos L, Narwal R. Baverel PG, et al. Among authors: zheng y. Clin Pharmacol Ther. 2018 Apr;103(4):631-642. doi: 10.1002/cpt.982. Epub 2018 Feb 2. Clin Pharmacol Ther. 2018. PMID: 29243223 Free PMC article.

3

Tumor Drug Penetration Measurements Could Be the Neglected Piece of the Personalized Cancer Treatment Puzzle.

Bartelink IH, Jones EF, Shahidi-Latham SK, Lee PRE, Zheng Y, Vicini P, van 't Veer L, Wolf D, Iagaru A, Kroetz DL, Prideaux B, Cilliers C, Thurber GM, Wimana Z, Gebhart G. Bartelink IH, et al. Among authors: zheng y. Clin Pharmacol Ther. 2019 Jul;106(1):148-163. doi: 10.1002/cpt.1211. Epub 2018 Oct 6. Clin Pharmacol Ther. 2019. PMID: 30107040 Free PMC article. Review.

4

Prognostic Significance of Liver Metastasis in Durvalumab-Treated Lung Cancer Patients.

Sridhar S, Paz-Ares L, Liu H, Shen K, Morehouse C, Rizvi N, Segal NH, Jin X, Zheng Y, Narwal R, Gupta A, Dennis PA, Ye J, Mukhopadhyay P, Higgs BW, Ranade K. Sridhar S, et al. Among authors: zheng y. Clin Lung Cancer. 2019 Nov;20(6):e601-e608. doi: 10.1016/j.cllc.2019.06.020. Epub 2019 Jun 26. Clin Lung Cancer. 2019. PMID: 31327642 Free article. Clinical Trial.

5

Progress and Opportunities to Advance Clinical Cancer Therapeutics Using Tumor Dynamic Models.

Bruno R, Bottino D, de Alwis DP, Fojo AT, Guedj J, Liu C, Swanson KR, Zheng J, Zheng Y, Jin JY. Bruno R, et al. Among authors: zheng j, zheng y. Clin Cancer Res. 2020 Apr 15;26(8):1787-1795. doi: 10.1158/1078-0432.CCR-19-0287. Epub 2019 Dec 23. Clin Cancer Res. 2020. PMID: 31871299 Free PMC article. Review.

6

Pharmacokinetic and Pharmacodynamic Modeling of Tezepelumab to Guide Phase 3 Dose Selection for Patients With Severe Asthma.

Ly N, Zheng Y, Griffiths JM, van der Merwe R, Agoram B, Parnes JR, Roskos L. Ly N, et al. Among authors: zheng y. J Clin Pharmacol. 2021 Jul;61(7):901-912. doi: 10.1002/jcph.1803. Epub 2021 Jan 16. J Clin Pharmacol. 2021. PMID: 33368307 Clinical Trial.

7

Population pharmacokinetic modelling of tremelimumab in patients with advanced solid tumours and the impact of disease status on time-varying clearance.

Hwang M, Chia YL, Zheng Y, Chen CC, He J, Song X, Zhou D, Goldberg SB, Siu LL, Planchard D, Peters S, Mann H, Krug L, Even C. Hwang M, et al. Among authors: zheng y. Br J Clin Pharmacol. 2023 May;89(5):1601-1616. doi: 10.1111/bcp.15622. Epub 2022 Dec 25. Br J Clin Pharmacol. 2023. PMID: 36454221 Free article.

8

Comparison of sequential and joint nonlinear mixed effects modeling of tumor kinetics and survival following Durvalumab treatment in patients with metastatic urothelial carcinoma.

Chen T, Zheng Y, Roskos L, Mager DE. Chen T, et al. Among authors: zheng y. J Pharmacokinet Pharmacodyn. 2023 Aug;50(4):251-265. doi: 10.1007/s10928-023-09848-w. Epub 2023 Mar 12. J Pharmacokinet Pharmacodyn. 2023. PMID: 36906878

9

Population Pharmacokinetic Modeling and Exposure-Efficacy and Body Weight-Response Analyses for Tezepelumab in Patients With Severe, Uncontrolled Asthma.

Zheng Y, Abuqayyas L, Quartino A, Guan Y, Gao Y, Liu L, Hellqvist Å, Colice G, MacDonald A. Zheng Y, et al. J Clin Pharmacol. 2024 Aug;64(8):908-921. doi: 10.1002/jcph.2433. Epub 2024 Apr 17. J Clin Pharmacol. 2024. PMID: 38632826 Clinical Trial.

10

Translational pharmacokinetics and pharmacodynamics of an FcRn-variant anti-CD4 monoclonal antibody from preclinical model to phase I study.

Zheng Y, Scheerens H, Davis JC Jr, Deng R, Fischer SK, Woods C, Fielder PJ, Stefanich EG. Zheng Y, et al. Clin Pharmacol Ther. 2011 Feb;89(2):283-90. doi: 10.1038/clpt.2010.311. Epub 2010 Dec 29. Clin Pharmacol Ther. 2011. PMID: 21191378 Clinical Trial.

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