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From benchtop to pilot scale-experimental study and computational assessment of a hot-melt extrusion scale-up of a solid dispersion of dipyridamole and copovidone.
Int J Pharm. 2018 Feb 15;537(1-2):132-139. doi: 10.1016/j.ijpharm.2017.12.033. Epub 2017 Dec 15.
Int J Pharm. 2018.
PMID: 29253586
Rational development of solid dispersions via hot-melt extrusion using screening, material characterization, and numeric simulation tools.
Zecevic DE, Wagner KG.
Zecevic DE, et al.
J Pharm Sci. 2013 Jul;102(7):2297-310. doi: 10.1002/jps.23592. Epub 2013 May 9.
J Pharm Sci. 2013.
PMID: 23661396
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In vivo predictive mini-scale dissolution for weak bases: Advantages of pH-shift in combination with an absorptive compartment.
Frank KJ, Locher K, Zecevic DE, Fleth J, Wagner KG.
Frank KJ, et al. Among authors: zecevic de.
Eur J Pharm Sci. 2014 Sep 30;61:32-9. doi: 10.1016/j.ejps.2013.12.015. Epub 2014 Jan 8.
Eur J Pharm Sci. 2014.
PMID: 24413061
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Site specific solubility improvement using solid dispersions of HPMC-AS/HPC SSL--mixtures.
Zecevic DE, Meier R, Daniels R, Wagner KG.
Zecevic DE, et al.
Eur J Pharm Biopharm. 2014 Jul;87(2):264-70. doi: 10.1016/j.ejpb.2014.03.018. Epub 2014 Apr 21.
Eur J Pharm Biopharm. 2014.
PMID: 24768770
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