O'Neill LAJ - Search Results

1

GSTO1-1 plays a pro-inflammatory role in models of inflammation, colitis and obesity.

Menon D, Innes A, Oakley AJ, Dahlstrom JE, Jensen LM, Brüstle A, Tummala P, Rooke M, Casarotto MG, Baell JB, Nguyen N, Xie Y, Cuellar M, Strasser J, Dahlin JL, Walters MA, Burgio G, O'Neill LAJ, Board PG. Menon D, et al. Sci Rep. 2017 Dec 19;7(1):17832. doi: 10.1038/s41598-017-17861-6. Sci Rep. 2017. PMID: 29259211 Free PMC article.

2

miR-107: a toll-like receptor-regulated miRNA dysregulated in obesity and type II diabetes.

Foley NH, O'Neill LA. Foley NH, et al. J Leukoc Biol. 2012 Sep;92(3):521-7. doi: 10.1189/jlb.0312160. Epub 2012 May 29. J Leukoc Biol. 2012. PMID: 22645244 Review.

3

Glutathione transferase omega 1 is required for the lipopolysaccharide-stimulated induction of NADPH oxidase 1 and the production of reactive oxygen species in macrophages.

Menon D, Coll R, O'Neill LA, Board PG. Menon D, et al. Free Radic Biol Med. 2014 Aug;73:318-27. doi: 10.1016/j.freeradbiomed.2014.05.020. Epub 2014 May 27. Free Radic Biol Med. 2014. PMID: 24873723

4

GSTO1-1 modulates metabolism in macrophages activated through the LPS and TLR4 pathway.

Menon D, Coll R, O'Neill LA, Board PG. Menon D, et al. J Cell Sci. 2015 May 15;128(10):1982-90. doi: 10.1242/jcs.167858. Epub 2015 Apr 23. J Cell Sci. 2015. PMID: 25908843

5

A Metabolic Roadblock in Inflammatory Macrophages.

O'Neill LA. O'Neill LA. Cell Rep. 2016 Oct 11;17(3):625-626. doi: 10.1016/j.celrep.2016.09.085. Cell Rep. 2016. PMID: 27732839 Free article.

6

The Induction of Pro-IL-1β by Lipopolysaccharide Requires Endogenous Prostaglandin E₂ Production.

Zasłona Z, Pålsson-McDermott EM, Menon D, Haneklaus M, Flis E, Prendeville H, Corcoran SE, Peters-Golden M, O'Neill LAJ. Zasłona Z, et al. J Immunol. 2017 May 1;198(9):3558-3564. doi: 10.4049/jimmunol.1602072. Epub 2017 Mar 15. J Immunol. 2017. PMID: 28298525

7

Macrophage Immunometabolism: Where Are We (Going)?

Van den Bossche J, O'Neill LA, Menon D. Van den Bossche J, et al. Trends Immunol. 2017 Jun;38(6):395-406. doi: 10.1016/j.it.2017.03.001. Epub 2017 Apr 7. Trends Immunol. 2017. PMID: 28396078 Review.

8

Solution structure of the TLR adaptor MAL/TIRAP reveals an intact BB loop and supports MAL Cys91 glutathionylation for signaling.

Hughes MM, Lavrencic P, Coll RC, Ve T, Ryan DG, Williams NC, Menon D, Mansell A, Board PG, Mobli M, Kobe B, O'Neill LAJ. Hughes MM, et al. Proc Natl Acad Sci U S A. 2017 Aug 8;114(32):E6480-E6489. doi: 10.1073/pnas.1701868114. Epub 2017 Jul 24. Proc Natl Acad Sci U S A. 2017. PMID: 28739909 Free PMC article.

9

Pyruvate Kinase M2 Is Required for the Expression of the Immune Checkpoint PD-L1 in Immune Cells and Tumors.

Palsson-McDermott EM, Dyck L, Zasłona Z, Menon D, McGettrick AF, Mills KHG, O'Neill LA. Palsson-McDermott EM, et al. Front Immunol. 2017 Oct 13;8:1300. doi: 10.3389/fimmu.2017.01300. eCollection 2017. Front Immunol. 2017. PMID: 29081778 Free PMC article.

10

Circadian clock protein BMAL1 regulates IL-1β in macrophages via NRF2.

Early JO, Menon D, Wyse CA, Cervantes-Silva MP, Zaslona Z, Carroll RG, Palsson-McDermott EM, Angiari S, Ryan DG, Corcoran SE, Timmons G, Geiger SS, Fitzpatrick DJ, O'Connell D, Xavier RJ, Hokamp K, O'Neill LAJ, Curtis AM. Early JO, et al. Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):E8460-E8468. doi: 10.1073/pnas.1800431115. Epub 2018 Aug 20. Proc Natl Acad Sci U S A. 2018. PMID: 30127006 Free PMC article.

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