Roberts CWM - Search Results

1

AP-1 Transcription Factors and the BAF Complex Mediate Signal-Dependent Enhancer Selection.

Vierbuchen T, Ling E, Cowley CJ, Couch CH, Wang X, Harmin DA, Roberts CWM, Greenberg ME. Vierbuchen T, et al. Among authors: roberts cwm. Mol Cell. 2017 Dec 21;68(6):1067-1082.e12. doi: 10.1016/j.molcel.2017.11.026. Mol Cell. 2017. PMID: 29272704 Free PMC article.

2

Highly penetrant, rapid tumorigenesis through conditional inversion of the tumor suppressor gene Snf5.

Roberts CW, Leroux MM, Fleming MD, Orkin SH. Roberts CW, et al. Cancer Cell. 2002 Nov;2(5):415-25. doi: 10.1016/s1535-6108(02)00185-x. Cancer Cell. 2002. PMID: 12450796 Free article.

3

Oncogenesis caused by loss of the SNF5 tumor suppressor is dependent on activity of BRG1, the ATPase of the SWI/SNF chromatin remodeling complex.

Wang X, Sansam CG, Thom CS, Metzger D, Evans JA, Nguyen PT, Roberts CW. Wang X, et al. Cancer Res. 2009 Oct 15;69(20):8094-101. doi: 10.1158/0008-5472.CAN-09-0733. Epub 2009 Sep 29. Cancer Res. 2009. PMID: 19789351 Free PMC article.

4

Epigenetic antagonism between polycomb and SWI/SNF complexes during oncogenic transformation.

Wilson BG, Wang X, Shen X, McKenna ES, Lemieux ME, Cho YJ, Koellhoffer EC, Pomeroy SL, Orkin SH, Roberts CW. Wilson BG, et al. Cancer Cell. 2010 Oct 19;18(4):316-28. doi: 10.1016/j.ccr.2010.09.006. Cancer Cell. 2010. PMID: 20951942 Free PMC article.

5

SWI/SNF nucleosome remodellers and cancer.

Wilson BG, Roberts CW. Wilson BG, et al. Nat Rev Cancer. 2011 Jun 9;11(7):481-92. doi: 10.1038/nrc3068. Nat Rev Cancer. 2011. PMID: 21654818 Review.

6

Epigenetic inactivation of the tumor suppressor BIN1 drives proliferation of SNF5-deficient tumors.

McKenna ES, Tamayo P, Cho YJ, Tillman EJ, Mora-Blanco EL, Sansam CG, Koellhoffer EC, Pomeroy SL, Roberts CW. McKenna ES, et al. Cell Cycle. 2012 May 15;11(10):1956-65. doi: 10.4161/cc.20280. Epub 2012 May 15. Cell Cycle. 2012. PMID: 22544318 Free PMC article.

7

Swi/Snf chromatin remodeling/tumor suppressor complex establishes nucleosome occupancy at target promoters.

Tolstorukov MY, Sansam CG, Lu P, Koellhoffer EC, Helming KC, Alver BH, Tillman EJ, Evans JA, Wilson BG, Park PJ, Roberts CW. Tolstorukov MY, et al. Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):10165-70. doi: 10.1073/pnas.1302209110. Epub 2013 May 30. Proc Natl Acad Sci U S A. 2013. PMID: 23723349 Free PMC article.

8

Molecular pathways: SWI/SNF (BAF) complexes are frequently mutated in cancer--mechanisms and potential therapeutic insights.

Wang X, Haswell JR, Roberts CW. Wang X, et al. Clin Cancer Res. 2014 Jan 1;20(1):21-7. doi: 10.1158/1078-0432.CCR-13-0280. Epub 2013 Oct 11. Clin Cancer Res. 2014. PMID: 24122795 Free PMC article.

9

The SWI/SNF tumor suppressor complex: Regulation of promoter nucleosomes and beyond.

Lu P, Roberts CW. Lu P, et al. Nucleus. 2013 Sep-Oct;4(5):374-8. doi: 10.4161/nucl.26654. Epub 2013 Sep 30. Nucleus. 2013. PMID: 24145903 Free PMC article. Review.

10

Linking the SWI/SNF complex to prostate cancer.

Lee RS, Roberts CW. Lee RS, et al. Nat Genet. 2013 Nov;45(11):1268-9. doi: 10.1038/ng.2805. Nat Genet. 2013. PMID: 24165726

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