D'Assoro A - Search Results

1

Phase I trial to evaluate the addition of alisertib to fulvestrant in women with endocrine-resistant, ER+ metastatic breast cancer.

Haddad TC, D'Assoro A, Suman V, Opyrchal M, Peethambaram P, Liu MC, Goetz MP, Ingle JN. Haddad TC, et al. Among authors: d assoro a. Breast Cancer Res Treat. 2018 Apr;168(3):639-647. doi: 10.1007/s10549-017-4616-7. Epub 2017 Dec 30. Breast Cancer Res Treat. 2018. PMID: 29289986 Free PMC article. Clinical Trial.

2

Amplified centrosomes in breast cancer: a potential indicator of tumor aggressiveness.

D'Assoro AB, Barrett SL, Folk C, Negron VC, Boeneman K, Busby R, Whitehead C, Stivala F, Lingle WL, Salisbury JL. D'Assoro AB, et al. Breast Cancer Res Treat. 2002 Sep;75(1):25-34. doi: 10.1023/a:1016550619925. Breast Cancer Res Treat. 2002. PMID: 12500932

3

Abrogation of p53 function leads to metastatic transcriptome networks that typify tumor progression in human breast cancer xenografts.

D'Assoro AB, Leontovich A, Amato A, Ayers-Ringler JR, Quatraro C, Hafner K, Jenkins RB, Libra M, Ingle J, Stivala F, Galanis E, Salisbury JL. D'Assoro AB, et al. Int J Oncol. 2010 Nov;37(5):1167-76. doi: 10.3892/ijo_00000768. Int J Oncol. 2010. PMID: 20878064 Free PMC article.

4

Raf-1 oncogenic signaling is linked to activation of mesenchymal to epithelial transition pathway in metastatic breast cancer cells.

Leontovich AA, Zhang S, Quatraro C, Iankov I, Veroux PF, Gambino MW, Degnim A, McCubrey J, Ingle J, Galanis E, D'Assoro AB. Leontovich AA, et al. Int J Oncol. 2012 Jun;40(6):1858-64. doi: 10.3892/ijo.2012.1407. Epub 2012 Mar 19. Int J Oncol. 2012. PMID: 22447278 Free PMC article.

5

The mitotic kinase Aurora--a promotes distant metastases by inducing epithelial-to-mesenchymal transition in ERα(+) breast cancer cells.

D'Assoro AB, Liu T, Quatraro C, Amato A, Opyrchal M, Leontovich A, Ikeda Y, Ohmine S, Lingle W, Suman V, Ecsedy J, Iankov I, Di Leonardo A, Ayers-Inglers J, Degnim A, Billadeau D, McCubrey J, Ingle J, Salisbury JL, Galanis E. D'Assoro AB, et al. Oncogene. 2014 Jan 30;33(5):599-610. doi: 10.1038/onc.2012.628. Epub 2013 Jan 21. Oncogene. 2014. PMID: 23334326 Free PMC article.

6

Inhibition of Cdk2 activity decreases Aurora-A kinase centrosomal localization and prevents centrosome amplification in breast cancer cells.

Leontovich AA, Salisbury JL, Veroux M, Tallarita T, Billadeau D, McCubrey J, Ingle J, Galanis E, D'Assoro AB. Leontovich AA, et al. Oncol Rep. 2013 May;29(5):1785-8. doi: 10.3892/or.2013.2313. Epub 2013 Feb 27. Oncol Rep. 2013. PMID: 23446853 Free PMC article.

7

Aurora-A mitotic kinase induces endocrine resistance through down-regulation of ERα expression in initially ERα+ breast cancer cells.

Opyrchal M, Salisbury JL, Zhang S, McCubrey J, Hawse J, Goetz MP, Lomberk GA, Haddad T, Degnim A, Lange C, Ingle JN, Galanis E, D'Assoro AB. Opyrchal M, et al. PLoS One. 2014 May 9;9(5):e96995. doi: 10.1371/journal.pone.0096995. eCollection 2014. PLoS One. 2014. PMID: 24816249 Free PMC article.

8

Inhibition of Cdk2 kinase activity selectively targets the CD44⁺/CD24⁻/Low stem-like subpopulation and restores chemosensitivity of SUM149PT triple-negative breast cancer cells.

Opyrchal M, Salisbury JL, Iankov I, Goetz MP, McCubrey J, Gambino MW, Malatino L, Puccia G, Ingle JN, Galanis E, D'Assoro AB. Opyrchal M, et al. Int J Oncol. 2014 Sep;45(3):1193-9. doi: 10.3892/ijo.2014.2523. Epub 2014 Jun 25. Int J Oncol. 2014. PMID: 24970653 Free PMC article.

9

Inhibition of the Aurora A kinase augments the anti-tumor efficacy of oncolytic measles virotherapy.

Iankov ID, Kurokawa CB, D'Assoro AB, Ingle JN, Domingo-Musibay E, Allen C, Crosby CM, Nair AA, Liu MC, Aderca I, Federspiel MJ, Galanis E. Iankov ID, et al. Cancer Gene Ther. 2015 Sep;22(9):438-44. doi: 10.1038/cgt.2015.36. Epub 2015 Aug 14. Cancer Gene Ther. 2015. PMID: 26272026 Free PMC article.

10

Aurora-A Kinase as a Promising Therapeutic Target in Cancer.

D'Assoro AB, Haddad T, Galanis E. D'Assoro AB, et al. Front Oncol. 2016 Jan 6;5:295. doi: 10.3389/fonc.2015.00295. eCollection 2015. Front Oncol. 2016. PMID: 26779440 Free PMC article. Review.

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