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Page 1
Discovery of selective, orally bioavailable inhibitor of mouse chitotriosidase.
Mazur M, Bartoszewicz A, Dymek B, Salamon M, Andryianau G, Kowalski M, Olejniczak S, Matyszewski K, Pluta E, Borek B, Stefaniak F, Zagozdzon A, Mazurkiewicz M, Koralewski R, Czestkowski W, Piotrowicz M, Niedziejko P, Gruza MM, Dzwonek K, Golebiowski A, Golab J, Olczak J. Mazur M, et al. Among authors: mazurkiewicz m. Bioorg Med Chem Lett. 2018 Feb 1;28(3):310-314. doi: 10.1016/j.bmcl.2017.12.047. Epub 2017 Dec 22. Bioorg Med Chem Lett. 2018. PMID: 29292229
Development of Dual Chitinase Inhibitors as Potential New Treatment for Respiratory System Diseases.
Mazur M, Dymek B, Koralewski R, Sklepkiewicz P, Olejniczak S, Mazurkiewicz M, Piotrowicz M, Salamon M, Jędrzejczak K, Zagozdzon A, Czestkowski W, Matyszewski K, Borek B, Bartoszewicz A, Pluta E, Rymaszewska A, Mozga W, Stefaniak F, Dobrzański P, Dzwonek K, Golab J, Golebiowski A, Olczak J. Mazur M, et al. Among authors: mazurkiewicz m. J Med Chem. 2019 Aug 8;62(15):7126-7145. doi: 10.1021/acs.jmedchem.9b00681. Epub 2019 Jul 23. J Med Chem. 2019. PMID: 31291098
Discovery of OATD-01, a First-in-Class Chitinase Inhibitor as Potential New Therapeutics for Idiopathic Pulmonary Fibrosis.
Koralewski R, Dymek B, Mazur M, Sklepkiewicz P, Olejniczak S, Czestkowski W, Matyszewski K, Andryianau G, Niedziejko P, Kowalski M, Gruza M, Borek B, Jedrzejczak K, Bartoszewicz A, Pluta E, Rymaszewska A, Kania M, Rejczak T, Piasecka S, Mlacki M, Mazurkiewicz M, Piotrowicz M, Salamon M, Zagozdzon A, Napiorkowska-Gromadzka A, Bartlomiejczak A, Mozga W, Dobrzański P, Dzwonek K, Golab J, Nowotny M, Olczak J, Golebiowski A. Koralewski R, et al. Among authors: mazurkiewicz m. J Med Chem. 2020 Dec 24;63(24):15527-15540. doi: 10.1021/acs.jmedchem.0c01179. Epub 2020 Oct 20. J Med Chem. 2020. PMID: 33078933
Inhibition of Macrophage-Specific CHIT1 as an Approach to Treat Airway Remodeling in Severe Asthma.
Sklepkiewicz P, Dymek B, Mlacki M, Zagozdzon A, Salamon M, Siwińska AM, Mazurkiewicz MP, de Souza Xavier Costa N, Mazur M, Mauad T, Gołębiowski A, Dzwonek K, Gołąb J, Zasłona Z. Sklepkiewicz P, et al. Among authors: mazurkiewicz mp. Int J Mol Sci. 2023 Mar 1;24(5):4719. doi: 10.3390/ijms24054719. Int J Mol Sci. 2023. PMID: 36902148 Free PMC article.
The cholinergic system, nerve growth factor and the cytoskeleton.
Niewiadomska G, Mietelska-Porowska A, Mazurkiewicz M. Niewiadomska G, et al. Among authors: mazurkiewicz m. Behav Brain Res. 2011 Aug 10;221(2):515-26. doi: 10.1016/j.bbr.2010.02.024. Epub 2010 Feb 16. Behav Brain Res. 2011. PMID: 20170684 Review.
Different pathways of molecular pathophysiology underlie cognitive and motor tauopathy phenotypes in transgenic models for Alzheimer's disease and frontotemporal lobar degeneration.
Melis V, Zabke C, Stamer K, Magbagbeolu M, Schwab K, Marschall P, Veh RW, Bachmann S, Deiana S, Moreau PH, Davidson K, Harrington KA, Rickard JE, Horsley D, Garman R, Mazurkiewicz M, Niewiadomska G, Wischik CM, Harrington CR, Riedel G, Theuring F. Melis V, et al. Among authors: mazurkiewicz m. Cell Mol Life Sci. 2015 Jun;72(11):2199-222. doi: 10.1007/s00018-014-1804-z. Epub 2014 Dec 19. Cell Mol Life Sci. 2015. PMID: 25523019 Free PMC article.
Surgical and non-surgical risk factors affecting the insufficiency of ileocolic anastomosis after first-time surgery in Crohn's disease patients.
Cwaliński J, Lorek F, Mazurkiewicz Ł, Mazurkiewicz M, Lizurej W, Paszkowski J, Cholerzyńska H, Zasada W. Cwaliński J, et al. Among authors: mazurkiewicz m. World J Gastrointest Surg. 2024 Oct 27;16(10):3253-3260. doi: 10.4240/wjgs.v16.i10.3253. World J Gastrointest Surg. 2024. PMID: 39575265 Free PMC article.
150 results