Mazharian A - Search Results

1

Maintenance of murine platelet homeostasis by the kinase Csk and phosphatase CD148.

Mori J, Nagy Z, Di Nunzio G, Smith CW, Geer MJ, Al Ghaithi R, van Geffen JP, Heising S, Boothman L, Tullemans BME, Correia JN, Tee L, Kuijpers MJE, Harrison P, Heemskerk JWM, Jarvis GE, Tarakhovsky A, Weiss A, Mazharian A, Senis YA. Mori J, et al. Among authors: mazharian a. Blood. 2018 Mar 8;131(10):1122-1144. doi: 10.1182/blood-2017-02-768077. Epub 2018 Jan 4. Blood. 2018. PMID: 29301754 Free PMC article.

2

The tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosis.

Senis YA, Tomlinson MG, Ellison S, Mazharian A, Lim J, Zhao Y, Kornerup KN, Auger JM, Thomas SG, Dhanjal T, Kalia N, Zhu JW, Weiss A, Watson SP. Senis YA, et al. Among authors: mazharian a. Blood. 2009 May 14;113(20):4942-54. doi: 10.1182/blood-2008-08-174318. Epub 2009 Feb 25. Blood. 2009. PMID: 19246339 Free PMC article.

3

Critical role of Src-Syk-PLC{gamma}2 signaling in megakaryocyte migration and thrombopoiesis.

Mazharian A, Thomas SG, Dhanjal TS, Buckley CD, Watson SP. Mazharian A, et al. Blood. 2010 Aug 5;116(5):793-800. doi: 10.1182/blood-2010-03-275990. Epub 2010 May 10. Blood. 2010. PMID: 20457868 Free article.

4

Dasatinib enhances megakaryocyte differentiation but inhibits platelet formation.

Mazharian A, Ghevaert C, Zhang L, Massberg S, Watson SP. Mazharian A, et al. Blood. 2011 May 12;117(19):5198-206. doi: 10.1182/blood-2010-12-326850. Epub 2011 Mar 8. Blood. 2011. PMID: 21385851 Free PMC article.

5

Mice lacking the ITIM-containing receptor G6b-B exhibit macrothrombocytopenia and aberrant platelet function.

Mazharian A, Wang YJ, Mori J, Bem D, Finney B, Heising S, Gissen P, White JG, Berndt MC, Gardiner EE, Nieswandt B, Douglas MR, Campbell RD, Watson SP, Senis YA. Mazharian A, et al. Sci Signal. 2012 Oct 30;5(248):ra78. doi: 10.1126/scisignal.2002936. Sci Signal. 2012. PMID: 23112346 Free PMC article.

6

Megakaryocyte-specific deletion of the protein-tyrosine phosphatases Shp1 and Shp2 causes abnormal megakaryocyte development, platelet production, and function.

Mazharian A, Mori J, Wang YJ, Heising S, Neel BG, Watson SP, Senis YA. Mazharian A, et al. Blood. 2013 May 16;121(20):4205-20. doi: 10.1182/blood-2012-08-449272. Epub 2013 Mar 18. Blood. 2013. PMID: 23509158 Free PMC article.

7

Sphingosine kinase 2 (Sphk2) regulates platelet biogenesis by providing intracellular sphingosine 1-phosphate (S1P).

Zhang L, Urtz N, Gaertner F, Legate KR, Petzold T, Lorenz M, Mazharian A, Watson SP, Massberg S. Zhang L, et al. Among authors: mazharian a. Blood. 2013 Aug 1;122(5):791-802. doi: 10.1182/blood-2012-12-473884. Epub 2013 Jun 17. Blood. 2013. PMID: 23775711 Free article.

8

JAK2V617F leads to intrinsic changes in platelet formation and reactivity in a knock-in mouse model of essential thrombocythemia.

Hobbs CM, Manning H, Bennett C, Vasquez L, Severin S, Brain L, Mazharian A, Guerrero JA, Li J, Soranzo N, Green AR, Watson SP, Ghevaert C. Hobbs CM, et al. Among authors: mazharian a. Blood. 2013 Nov 28;122(23):3787-97. doi: 10.1182/blood-2013-06-501452. Epub 2013 Oct 1. Blood. 2013. PMID: 24085768 Free PMC article.

9

Src family kinases: at the forefront of platelet activation.

Senis YA, Mazharian A, Mori J. Senis YA, et al. Among authors: mazharian a. Blood. 2014 Sep 25;124(13):2013-24. doi: 10.1182/blood-2014-01-453134. Epub 2014 Aug 12. Blood. 2014. PMID: 25115887 Free PMC article. Review.

10

Proplatelets slip slidin' away.

Mazharian A, Senis YA. Mazharian A, et al. Blood. 2015 Jan 29;125(5):747-8. doi: 10.1182/blood-2014-12-614131. Blood. 2015. PMID: 25634614 Free article.

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