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Structural heterogeneity and intersubject variability of Aβ in familial and sporadic Alzheimer's disease.
Condello C, Lemmin T, Stöhr J, Nick M, Wu Y, Maxwell AM, Watts JC, Caro CD, Oehler A, Keene CD, Bird TD, van Duinen SG, Lannfelt L, Ingelsson M, Graff C, Giles K, DeGrado WF, Prusiner SB. Condello C, et al. Among authors: lemmin t. Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):E782-E791. doi: 10.1073/pnas.1714966115. Epub 2018 Jan 8. Proc Natl Acad Sci U S A. 2018. PMID: 29311311 Free PMC article.
Designed metalloprotein stabilizes a semiquinone radical.
Ulas G, Lemmin T, Wu Y, Gassner GT, DeGrado WF. Ulas G, et al. Among authors: lemmin t. Nat Chem. 2016 Apr;8(4):354-9. doi: 10.1038/nchem.2453. Epub 2016 Feb 15. Nat Chem. 2016. PMID: 27001731 Free PMC article.
XFEL structures of the influenza M2 proton channel: Room temperature water networks and insights into proton conduction.
Thomaston JL, Woldeyes RA, Nakane T, Yamashita A, Tanaka T, Koiwai K, Brewster AS, Barad BA, Chen Y, Lemmin T, Uervirojnangkoorn M, Arima T, Kobayashi J, Masuda T, Suzuki M, Sugahara M, Sauter NK, Tanaka R, Nureki O, Tono K, Joti Y, Nango E, Iwata S, Yumoto F, Fraser JS, DeGrado WF. Thomaston JL, et al. Among authors: lemmin t. Proc Natl Acad Sci U S A. 2017 Dec 19;114(51):13357-13362. doi: 10.1073/pnas.1705624114. Epub 2017 Aug 23. Proc Natl Acad Sci U S A. 2017. PMID: 28835537 Free PMC article.
A 31-residue peptide induces aggregation of tau's microtubule-binding region in cells.
Stöhr J, Wu H, Nick M, Wu Y, Bhate M, Condello C, Johnson N, Rodgers J, Lemmin T, Acharya S, Becker J, Robinson K, Kelly MJS, Gai F, Stubbs G, Prusiner SB, DeGrado WF. Stöhr J, et al. Among authors: lemmin t. Nat Chem. 2017 Sep;9(9):874-881. doi: 10.1038/nchem.2754. Epub 2017 Apr 3. Nat Chem. 2017. PMID: 28837163 Free PMC article.
45 results