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Interfering with HuR-RNA Interaction: Design, Synthesis and Biological Characterization of Tanshinone Mimics as Novel, Effective HuR Inhibitors.
Manzoni L, Zucal C, Maio DD, D'Agostino VG, Thongon N, Bonomo I, Lal P, Miceli M, Baj V, Brambilla M, Cerofolini L, Elezgarai S, Biasini E, Luchinat C, Novellino E, Fragai M, Marinelli L, Provenzani A, Seneci P. Manzoni L, et al. Among authors: marinelli l. J Med Chem. 2018 Feb 22;61(4):1483-1498. doi: 10.1021/acs.jmedchem.7b01176. Epub 2018 Jan 31. J Med Chem. 2018. PMID: 29313684
Synthesis, molecular modeling, and opioid receptor affinity of 9, 10-diazatricyclo[4.2.1.1(2,5)]decanes and 2,7-diazatricyclo[4.4.0. 0(3,8)]decanes structurally related to 3,8-diazabicyclo[3.2. 1]octanes.
Vianello P, Albinati A, Pinna GA, Lavecchia A, Marinelli L, Borea PA, Gessi S, Fadda P, Tronci S, Cignarella G. Vianello P, et al. Among authors: marinelli l. J Med Chem. 2000 Jun 1;43(11):2115-23. doi: 10.1021/jm991140q. J Med Chem. 2000. PMID: 10841790
Urotensin-II receptor ligands. From agonist to antagonist activity.
Grieco P, Carotenuto A, Campiglia P, Marinelli L, Lama T, Patacchini R, Santicioli P, Maggi CA, Rovero P, Novellino E. Grieco P, et al. Among authors: marinelli l. J Med Chem. 2005 Nov 17;48(23):7290-7. doi: 10.1021/jm058043j. J Med Chem. 2005. PMID: 16279788
Novel bifunctional quinolonyl diketo acid derivatives as HIV-1 integrase inhibitors: design, synthesis, biological activities, and mechanism of action.
Di Santo R, Costi R, Roux A, Artico M, Lavecchia A, Marinelli L, Novellino E, Palmisano L, Andreotti M, Amici R, Galluzzo CM, Nencioni L, Palamara AT, Pommier Y, Marchand C. Di Santo R, et al. Among authors: marinelli l. J Med Chem. 2006 Mar 23;49(6):1939-45. doi: 10.1021/jm0511583. J Med Chem. 2006. PMID: 16539381 Free PMC article.
663 results