Sarkaria JN - Search Results

1

Phase 1/2 trial of temsirolimus and sorafenib in the treatment of patients with recurrent glioblastoma: North Central Cancer Treatment Group Study/Alliance N0572.

Schiff D, Jaeckle KA, Anderson SK, Galanis E, Giannini C, Buckner JC, Stella P, Flynn PJ, Erickson BJ, Schwerkoske JF, Kaluza V, Twohy E, Dancey J, Wright J, Sarkaria JN. Schiff D, et al. Among authors: sarkaria jn. Cancer. 2018 Apr 1;124(7):1455-1463. doi: 10.1002/cncr.31219. Epub 2018 Jan 3. Cancer. 2018. PMID: 29313954 Free PMC article. Clinical Trial.

2

Inhibition of the mammalian target of rapamycin sensitizes U87 xenografts to fractionated radiation therapy.

Eshleman JS, Carlson BL, Mladek AC, Kastner BD, Shide KL, Sarkaria JN. Eshleman JS, et al. Among authors: sarkaria jn. Cancer Res. 2002 Dec 15;62(24):7291-7. Cancer Res. 2002. PMID: 12499272

3

Mammalian target of rapamycin (mTOR) inhibitors as anti-cancer agents.

Rao RD, Buckner JC, Sarkaria JN. Rao RD, et al. Among authors: sarkaria jn. Curr Cancer Drug Targets. 2004 Dec;4(8):621-35. doi: 10.2174/1568009043332718. Curr Cancer Drug Targets. 2004. PMID: 15578919 Review.

4

Patient tumor EGFR and PDGFRA gene amplifications retained in an invasive intracranial xenograft model of glioblastoma multiforme.

Giannini C, Sarkaria JN, Saito A, Uhm JH, Galanis E, Carlson BL, Schroeder MA, James CD. Giannini C, et al. Among authors: sarkaria jn. Neuro Oncol. 2005 Apr;7(2):164-76. doi: 10.1215/S1152851704000821. Neuro Oncol. 2005. PMID: 15831234 Free PMC article.

5

Use of an orthotopic xenograft model for assessing the effect of epidermal growth factor receptor amplification on glioblastoma radiation response.

Sarkaria JN, Carlson BL, Schroeder MA, Grogan P, Brown PD, Giannini C, Ballman KV, Kitange GJ, Guha A, Pandita A, James CD. Sarkaria JN, et al. Clin Cancer Res. 2006 Apr 1;12(7 Pt 1):2264-71. doi: 10.1158/1078-0432.CCR-05-2510. Clin Cancer Res. 2006. PMID: 16609043

6

Cytotoxic synergy between the multikinase inhibitor sorafenib and the proteasome inhibitor bortezomib in vitro: induction of apoptosis through Akt and c-Jun NH2-terminal kinase pathways.

Yu C, Friday BB, Lai JP, Yang L, Sarkaria J, Kay NE, Carter CA, Roberts LR, Kaufmann SH, Adjei AA. Yu C, et al. Mol Cancer Ther. 2006 Sep;5(9):2378-87. doi: 10.1158/1535-7163.MCT-06-0235. Mol Cancer Ther. 2006. PMID: 16985072

7

Identification of molecular characteristics correlated with glioblastoma sensitivity to EGFR kinase inhibition through use of an intracranial xenograft test panel.

Sarkaria JN, Yang L, Grogan PT, Kitange GJ, Carlson BL, Schroeder MA, Galanis E, Giannini C, Wu W, Dinca EB, James CD. Sarkaria JN, et al. Mol Cancer Ther. 2007 Mar;6(3):1167-74. doi: 10.1158/1535-7163.MCT-06-0691. Mol Cancer Ther. 2007. PMID: 17363510

8

Phase I trial of sirolimus combined with radiation and cisplatin in non-small cell lung cancer.

Sarkaria JN, Schwingler P, Schild SE, Grogan PT, Mladek AC, Mandrekar SJ, Tan AD, Kobayashi T, Marks RS, Kita H, Miller RC, Limper AH, Leof EB. Sarkaria JN, et al. J Thorac Oncol. 2007 Aug;2(8):751-7. doi: 10.1097/JTO.0b013e3180cc2587. J Thorac Oncol. 2007. PMID: 17762343 Free article. Clinical Trial.

9

Combination of measles virus virotherapy and radiation therapy has synergistic activity in the treatment of glioblastoma multiforme.

Liu C, Sarkaria JN, Petell CA, Paraskevakou G, Zollman PJ, Schroeder M, Carlson B, Decker PA, Wu W, James CD, Russell SJ, Galanis E. Liu C, et al. Among authors: sarkaria jn. Clin Cancer Res. 2007 Dec 1;13(23):7155-65. doi: 10.1158/1078-0432.CCR-07-1306. Clin Cancer Res. 2007. PMID: 18056196

10

PTEN loss does not predict for response to RAD001 (Everolimus) in a glioblastoma orthotopic xenograft test panel.

Yang L, Clarke MJ, Carlson BL, Mladek AC, Schroeder MA, Decker P, Wu W, Kitange GJ, Grogan PT, Goble JM, Uhm J, Galanis E, Giannini C, Lane HA, James CD, Sarkaria JN. Yang L, et al. Among authors: sarkaria jn. Clin Cancer Res. 2008 Jun 15;14(12):3993-4001. doi: 10.1158/1078-0432.CCR-07-4152. Clin Cancer Res. 2008. PMID: 18559622 Free PMC article.

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