Jain S - Search Results

1

Hepatic Gi signaling regulates whole-body glucose homeostasis.

Rossi M, Zhu L, McMillin SM, Pydi SP, Jain S, Wang L, Cui Y, Lee RJ, Cohen AH, Kaneto H, Birnbaum MJ, Ma Y, Rotman Y, Liu J, Cyphert TJ, Finkel T, McGuinness OP, Wess J. Rossi M, et al. Among authors: jain s. J Clin Invest. 2018 Feb 1;128(2):746-759. doi: 10.1172/JCI94505. Epub 2018 Jan 16. J Clin Invest. 2018. PMID: 29337301 Free PMC article.

2

Adipocyte β-arrestin-2 is essential for maintaining whole body glucose and energy homeostasis.

Pydi SP, Jain S, Tung W, Cui Y, Zhu L, Sakamoto W, Jain S, Abel BS, Skarulis MC, Liu J, Huynh T, Pacak K, Caron MG, Gavrilova O, Finkel T, Wess J. Pydi SP, et al. Among authors: jain s. Nat Commun. 2019 Jul 3;10(1):2936. doi: 10.1038/s41467-019-11003-4. Nat Commun. 2019. PMID: 31270323 Free PMC article.

3

β-arrestin-1 suppresses myogenic reprogramming of brown fat to maintain euglycemia.

Pydi SP, Jain S, Barella LF, Zhu L, Sakamoto W, Meister J, Wang L, Lu H, Cui Y, Gavrilova O, Wess J. Pydi SP, et al. Among authors: jain s. Sci Adv. 2020 Jun 5;6(23):eaba1733. doi: 10.1126/sciadv.aba1733. eCollection 2020 Jun. Sci Adv. 2020. PMID: 32548266 Free PMC article.

4

Lack of adipocyte purinergic P2Y₆ receptor greatly improves whole body glucose homeostasis.

Jain S, Pydi SP, Toti KS, Robaye B, Idzko M, Gavrilova O, Wess J, Jacobson KA. Jain S, et al. Proc Natl Acad Sci U S A. 2020 Dec 1;117(48):30763-30774. doi: 10.1073/pnas.2006578117. Epub 2020 Nov 16. Proc Natl Acad Sci U S A. 2020. PMID: 33199639 Free PMC article.

5

Metabolic roles of G protein-coupled receptor signaling in obesity and type 2 diabetes.

Barella LF, Jain S, Kimura T, Pydi SP. Barella LF, et al. Among authors: jain s. FEBS J. 2021 Apr;288(8):2622-2644. doi: 10.1111/febs.15800. Epub 2021 Mar 22. FEBS J. 2021. PMID: 33682344 Free article. Review.

6

Adipocyte P2Y14 receptors play a key role in regulating whole-body glucose and lipid homeostasis.

Jain S, Pydi SP, Jung YH, Scortichini M, Kesner EL, Karcz TP, Cook DN, Gavrilova O, Wess J, Jacobson KA. Jain S, et al. JCI Insight. 2021 May 24;6(10):e146577. doi: 10.1172/jci.insight.146577. JCI Insight. 2021. PMID: 34027896 Free PMC article.

7

β-Arrestin-1 is required for adaptive β-cell mass expansion during obesity.

Barella LF, Rossi M, Pydi SP, Meister J, Jain S, Cui Y, Gavrilova O, Fulgenzi G, Tessarollo L, Wess J. Barella LF, et al. Among authors: jain s. Nat Commun. 2021 Jun 7;12(1):3385. doi: 10.1038/s41467-021-23656-1. Nat Commun. 2021. PMID: 34099679 Free PMC article.

8

Adenosine A₁ receptor is dispensable for hepatocyte glucose metabolism and insulin sensitivity.

Jain S, Barella LF, Wess J, Reitman ML, Jacobson KA. Jain S, et al. Biochem Pharmacol. 2021 Oct;192:114739. doi: 10.1016/j.bcp.2021.114739. Epub 2021 Aug 19. Biochem Pharmacol. 2021. PMID: 34418353 Free PMC article.

9

G protein-coupled receptors: Role in metabolic disorders.

Barella LF, Jain S, Pydi SP. Barella LF, et al. Among authors: jain s. Front Endocrinol (Lausanne). 2022 Aug 4;13:984253. doi: 10.3389/fendo.2022.984253. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 35992121 Free PMC article. No abstract available.

10

Design and in vivo activity of A₃ adenosine receptor agonist prodrugs.

Suresh RR, Jain S, Chen Z, Tosh DK, Ma Y, Podszun MC, Rotman Y, Salvemini D, Jacobson KA. Suresh RR, et al. Among authors: jain s. Purinergic Signal. 2020 Sep;16(3):367-377. doi: 10.1007/s11302-020-09715-0. Epub 2020 Jul 27. Purinergic Signal. 2020. PMID: 32720036 Free PMC article.

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