Lee RJ - Search Results

1

Hepatic Gi signaling regulates whole-body glucose homeostasis.

Rossi M, Zhu L, McMillin SM, Pydi SP, Jain S, Wang L, Cui Y, Lee RJ, Cohen AH, Kaneto H, Birnbaum MJ, Ma Y, Rotman Y, Liu J, Cyphert TJ, Finkel T, McGuinness OP, Wess J. Rossi M, et al. Among authors: lee rj. J Clin Invest. 2018 Feb 1;128(2):746-759. doi: 10.1172/JCI94505. Epub 2018 Jan 16. J Clin Invest. 2018. PMID: 29337301 Free PMC article.

2

Hepatic β-arrestin 2 is essential for maintaining euglycemia.

Zhu L, Rossi M, Cui Y, Lee RJ, Sakamoto W, Perry NA, Urs NM, Caron MG, Gurevich VV, Godlewski G, Kunos G, Chen M, Chen W, Wess J. Zhu L, et al. Among authors: lee rj. J Clin Invest. 2017 Aug 1;127(8):2941-2945. doi: 10.1172/JCI92913. Epub 2017 Jun 26. J Clin Invest. 2017. PMID: 28650340 Free PMC article.

3

Skeletal Muscle-Specific Activation of G_q Signaling Maintains Glucose Homeostasis.

Bone DBJ, Meister J, Knudsen JR, Dattaroy D, Cohen A, Lee R, Lu H, Metzger D, Jensen TE, Wess J. Bone DBJ, et al. Diabetes. 2019 Jun;68(6):1341-1352. doi: 10.2337/db18-0796. Epub 2019 Apr 1. Diabetes. 2019. PMID: 30936140 Free PMC article.

4

β-arrestin-2 is an essential regulator of pancreatic β-cell function under physiological and pathophysiological conditions.

Zhu L, Almaça J, Dadi PK, Hong H, Sakamoto W, Rossi M, Lee RJ, Vierra NC, Lu H, Cui Y, McMillin SM, Perry NA, Gurevich VV, Lee A, Kuo B, Leapman RD, Matschinsky FM, Doliba NM, Urs NM, Caron MG, Jacobson DA, Caicedo A, Wess J. Zhu L, et al. Among authors: lee rj, lee a. Nat Commun. 2017 Feb 1;8:14295. doi: 10.1038/ncomms14295. Nat Commun. 2017. PMID: 28145434 Free PMC article.

5

In vivo metabolic effects after acute activation of skeletal muscle G_s signaling.

Meister J, Bone DBJ, Knudsen JR, Barella LF, Liu L, Lee R, Gavrilova O, Chen M, Weinstein LS, Kleinert M, Jensen TE, Wess J. Meister J, et al. Mol Metab. 2022 Jan;55:101415. doi: 10.1016/j.molmet.2021.101415. Epub 2021 Dec 6. Mol Metab. 2022. PMID: 34883278 Free PMC article.

6

Clenbuterol exerts antidiabetic activity through metabolic reprogramming of skeletal muscle cells.

Meister J, Bone DBJ, Knudsen JR, Barella LF, Velenosi TJ, Akhmedov D, Lee RJ, Cohen AH, Gavrilova O, Cui Y, Karsenty G, Chen M, Weinstein LS, Kleinert M, Berdeaux R, Jensen TE, Richter EA, Wess J. Meister J, et al. Among authors: lee rj. Nat Commun. 2022 Jan 10;13(1):22. doi: 10.1038/s41467-021-27540-w. Nat Commun. 2022. PMID: 35013148 Free PMC article.

7

Metabolic effects of skeletal muscle-specific deletion of beta-arrestin-1 and -2 in mice.

Meister J, Bone DBJ, Godlewski G, Liu Z, Lee RJ, Vishnivetskiy SA, Gurevich VV, Springer D, Kunos G, Wess J. Meister J, et al. Among authors: lee rj. PLoS Genet. 2019 Oct 17;15(10):e1008424. doi: 10.1371/journal.pgen.1008424. eCollection 2019 Oct. PLoS Genet. 2019. PMID: 31622341 Free PMC article.

8

Paternal versus maternal transmission of a stimulatory G-protein alpha subunit knockout produces opposite effects on energy metabolism.

Yu S, Gavrilova O, Chen H, Lee R, Liu J, Pacak K, Parlow AF, Quon MJ, Reitman ML, Weinstein LS. Yu S, et al. J Clin Invest. 2000 Mar;105(5):615-23. doi: 10.1172/JCI8437. J Clin Invest. 2000. PMID: 10712433 Free PMC article.

9

Increased insulin sensitivity in Gsalpha knockout mice.

Yu S, Castle A, Chen M, Lee R, Takeda K, Weinstein LS. Yu S, et al. J Biol Chem. 2001 Jun 8;276(23):19994-8. doi: 10.1074/jbc.M010313200. Epub 2001 Mar 27. J Biol Chem. 2001. PMID: 11274197 Free article.

10

Variable and tissue-specific hormone resistance in heterotrimeric Gs protein alpha-subunit (Gsalpha) knockout mice is due to tissue-specific imprinting of the gsalpha gene.

Yu S, Yu D, Lee E, Eckhaus M, Lee R, Corria Z, Accili D, Westphal H, Weinstein LS. Yu S, et al. Proc Natl Acad Sci U S A. 1998 Jul 21;95(15):8715-20. doi: 10.1073/pnas.95.15.8715. Proc Natl Acad Sci U S A. 1998. PMID: 9671744 Free PMC article.

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