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163 results

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Standardisation of defined approaches for skin sensitisation testing to support regulatory use and international adoption: position of the International Cooperation on Alternative Test Methods.
Casati S, Aschberger K, Barroso J, Casey W, Delgado I, Kim TS, Kleinstreuer N, Kojima H, Lee JK, Lowit A, Park HK, Régimbald-Krnel MJ, Strickland J, Whelan M, Yang Y, Zuang V. Casati S, et al. Among authors: kleinstreuer n. Arch Toxicol. 2018 Feb;92(2):611-617. doi: 10.1007/s00204-017-2097-4. Epub 2017 Nov 10. Arch Toxicol. 2018. PMID: 29127450 Free PMC article.
Skin sensitization testing needs and data uses by US regulatory and research agencies.
Strickland J, Daniel AB, Allen D, Aguila C, Ahir S, Bancos S, Craig E, Germolec D, Ghosh C, Hudson NL, Jacobs A, Lehmann DM, Matheson J, Reinke EN, Sadrieh N, Vukmanovic S, Kleinstreuer N. Strickland J, et al. Among authors: kleinstreuer n. Arch Toxicol. 2019 Feb;93(2):273-291. doi: 10.1007/s00204-018-2341-6. Epub 2018 Oct 30. Arch Toxicol. 2019. PMID: 30377734 Free PMC article. Review.
FutureTox IV Workshop Summary: Predictive Toxicology for Healthy Children.
Knudsen TB, Fitzpatrick SC, De Abrew KN, Birnbaum LS, Chappelle A, Daston GP, Dolinoy DC, Elder A, Euling S, Faustman EM, Fedinick KP, Franzosa JA, Haggard DE, Haws L, Kleinstreuer NC, Buck Louis GM, Mendrick DL, Rudel R, Saili KS, Schug TT, Tanguay RL, Turley AE, Wetmore BA, White KW, Zurlinden TJ. Knudsen TB, et al. Toxicol Sci. 2021 Apr 12;180(2):198-211. doi: 10.1093/toxsci/kfab013. Toxicol Sci. 2021. PMID: 33555348 Free PMC article. Review.
New approach methodologies in human regulatory toxicology - Not if, but how and when!
Schmeisser S, Miccoli A, von Bergen M, Berggren E, Braeuning A, Busch W, Desaintes C, Gourmelon A, Grafström R, Harrill J, Hartung T, Herzler M, Kass GEN, Kleinstreuer N, Leist M, Luijten M, Marx-Stoelting P, Poetz O, van Ravenzwaay B, Roggeband R, Rogiers V, Roth A, Sanders P, Thomas RS, Marie Vinggaard A, Vinken M, van de Water B, Luch A, Tralau T. Schmeisser S, et al. Among authors: kleinstreuer n. Environ Int. 2023 Aug;178:108082. doi: 10.1016/j.envint.2023.108082. Epub 2023 Jul 4. Environ Int. 2023. PMID: 37422975 Free PMC article. Review.
Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets.
Knudsen TB, Houck KA, Sipes NS, Singh AV, Judson RS, Martin MT, Weissman A, Kleinstreuer NC, Mortensen HM, Reif DM, Rabinowitz JR, Setzer RW, Richard AM, Dix DJ, Kavlock RJ. Knudsen TB, et al. Toxicology. 2011 Mar 28;282(1-2):1-15. doi: 10.1016/j.tox.2010.12.010. Epub 2011 Jan 18. Toxicology. 2011. PMID: 21251949
Adverse outcome pathways: From research to regulation scientific workshop report.
Kleinstreuer NC, Sullivan K, Allen D, Edwards S, Mendrick DL, Embry M, Matheson J, Rowlands JC, Munn S, Maull E, Casey W. Kleinstreuer NC, et al. Regul Toxicol Pharmacol. 2016 Apr;76:39-50. doi: 10.1016/j.yrtph.2016.01.007. Epub 2016 Jan 14. Regul Toxicol Pharmacol. 2016. PMID: 26774756 Free PMC article.
In vitro to in vivo extrapolation for high throughput prioritization and decision making.
Bell SM, Chang X, Wambaugh JF, Allen DG, Bartels M, Brouwer KLR, Casey WM, Choksi N, Ferguson SS, Fraczkiewicz G, Jarabek AM, Ke A, Lumen A, Lynn SG, Paini A, Price PS, Ring C, Simon TW, Sipes NS, Sprankle CS, Strickland J, Troutman J, Wetmore BA, Kleinstreuer NC. Bell SM, et al. Among authors: kleinstreuer nc. Toxicol In Vitro. 2018 Mar;47:213-227. doi: 10.1016/j.tiv.2017.11.016. Epub 2017 Dec 5. Toxicol In Vitro. 2018. PMID: 29203341 Free PMC article. Review.
Non-animal methods to predict skin sensitization (II): an assessment of defined approaches *.
Kleinstreuer NC, Hoffmann S, Alépée N, Allen D, Ashikaga T, Casey W, Clouet E, Cluzel M, Desprez B, Gellatly N, Göbel C, Kern PS, Klaric M, Kühnl J, Martinozzi-Teissier S, Mewes K, Miyazawa M, Strickland J, van Vliet E, Zang Q, Petersohn D. Kleinstreuer NC, et al. Crit Rev Toxicol. 2018 May;48(5):359-374. doi: 10.1080/10408444.2018.1429386. Epub 2018 Feb 23. Crit Rev Toxicol. 2018. PMID: 29474122 Free PMC article. Review.
Non-animal methods to predict skin sensitization (I): the Cosmetics Europe database<sup/>
Hoffmann S, Kleinstreuer N, Alépée N, Allen D, Api AM, Ashikaga T, Clouet E, Cluzel M, Desprez B, Gellatly N, Goebel C, Kern PS, Klaric M, Kühnl J, Lalko JF, Martinozzi-Teissier S, Mewes K, Miyazawa M, Parakhia R, van Vliet E, Zang Q, Petersohn D. Hoffmann S, et al. Among authors: kleinstreuer n. Crit Rev Toxicol. 2018 May;48(5):344-358. doi: 10.1080/10408444.2018.1429385. Epub 2018 Feb 23. Crit Rev Toxicol. 2018. PMID: 29474128 Review.
163 results