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ELT-2 is the predominant transcription factor controlling differentiation and function of the C. elegans intestine, from embryo to adult.
McGhee JD, Fukushige T, Krause MW, Minnema SE, Goszczynski B, Gaudet J, Kohara Y, Bossinger O, Zhao Y, Khattra J, Hirst M, Jones SJ, Marra MA, Ruzanov P, Warner A, Zapf R, Moerman DG, Kalb JM. McGhee JD, et al. Dev Biol. 2009 Mar 15;327(2):551-65. doi: 10.1016/j.ydbio.2008.11.034. Epub 2008 Dec 9. Dev Biol. 2009. PMID: 19111532 Free PMC article.
A 44 bp intestine-specific hermaphrodite-specific enhancer from the C. elegans vit-2 vitellogenin gene is directly regulated by ELT-2, MAB-3, FKH-9 and DAF-16 and indirectly regulated by the germline, by daf-2/insulin signaling and by the TGF-β/Sma/Mab pathway.
Goszczynski B, Captan VV, Danielson AM, Lancaster BR, McGhee JD. Goszczynski B, et al. Among authors: mcghee jd. Dev Biol. 2016 May 1;413(1):112-27. doi: 10.1016/j.ydbio.2016.02.031. Epub 2016 Mar 7. Dev Biol. 2016. PMID: 26963674 Free article.
94 results