Qin H - Search Results

1

The miR-17/92 cluster is involved in the molecular etiology of the SCLL syndrome driven by the BCR-FGFR1 chimeric kinase.

Hu T, Chong Y, Qin H, Kitamura E, Chang CS, Silva J, Ren M, Cowell JK. Hu T, et al. Among authors: qin h. Oncogene. 2018 Apr;37(14):1926-1938. doi: 10.1038/s41388-017-0091-1. Epub 2018 Jan 25. Oncogene. 2018. PMID: 29367757 Free PMC article.

2

Ponatinib suppresses the development of myeloid and lymphoid malignancies associated with FGFR1 abnormalities.

Ren M, Qin H, Ren R, Cowell JK. Ren M, et al. Among authors: qin h. Leukemia. 2013 Jan;27(1):32-40. doi: 10.1038/leu.2012.188. Epub 2012 Jul 11. Leukemia. 2013. PMID: 22781593 Free PMC article.

3

Transformation of human CD34+ hematopoietic progenitor cells with DEK-NUP214 induces AML in an immunocompromised mouse model.

Qin H, Malek S, Cowell JK, Ren M. Qin H, et al. Oncogene. 2016 Oct 27;35(43):5686-5691. doi: 10.1038/onc.2016.118. Epub 2016 Apr 11. Oncogene. 2016. PMID: 27065320 Free PMC article.

4

Src activation plays an important key role in lymphomagenesis induced by FGFR1 fusion kinases.

Ren M, Qin H, Ren R, Tidwell J, Cowell JK. Ren M, et al. Among authors: qin h. Cancer Res. 2011 Dec 1;71(23):7312-22. doi: 10.1158/0008-5472.CAN-11-1109. Epub 2011 Sep 21. Cancer Res. 2011. PMID: 21937681 Free PMC article.

5

Dysregulated signaling pathways in the development of CNTRL-FGFR1-induced myeloid and lymphoid malignancies associated with FGFR1 in human and mouse models.

Ren M, Qin H, Kitamura E, Cowell JK. Ren M, et al. Among authors: qin h. Blood. 2013 Aug 8;122(6):1007-16. doi: 10.1182/blood-2013-03-489823. Epub 2013 Jun 18. Blood. 2013. PMID: 23777766 Free PMC article.

6

FGFR1OP2-FGFR1 induced myeloid leukemia and T-cell lymphoma in a mouse model.

Qin H, Wu Q, Cowell JK, Ren M. Qin H, et al. Haematologica. 2016 Mar;101(3):e91-4. doi: 10.3324/haematol.2015.137695. Epub 2015 Nov 20. Haematologica. 2016. PMID: 26589915 Free PMC article. No abstract available.

7

Development of ZMYM2-FGFR1 driven AML in human CD34+ cells in immunocompromised mice.

Ren M, Qin H, Wu Q, Savage NM, George TI, Cowell JK. Ren M, et al. Among authors: qin h. Int J Cancer. 2016 Aug 15;139(4):836-40. doi: 10.1002/ijc.30100. Epub 2016 May 4. Int J Cancer. 2016. PMID: 27005999 Free PMC article.

8

SCLLTargeting FGFR1 to suppress leukemogenesis in syndromic and de novo AML in murine models.

Wu Q, Bhole A, Qin H, Karp J, Malek S, Cowell JK, Ren M. Wu Q, et al. Among authors: qin h. Oncotarget. 2016 Aug 2;7(31):49733-49742. doi: 10.18632/oncotarget.10438. Oncotarget. 2016. PMID: 27391347 Free PMC article.

9

A model of BCR-FGFR1 driven human AML in immunocompromised mice.

Cowell JK, Qin H, Chang CS, Kitamura E, Ren M. Cowell JK, et al. Among authors: qin h. Br J Haematol. 2016 Nov;175(3):542-545. doi: 10.1111/bjh.13877. Epub 2015 Dec 21. Br J Haematol. 2016. PMID: 27785808 Free PMC article. No abstract available.

10

Mutation in the FGFR1 tyrosine kinase domain or inactivation of PTEN is associated with acquired resistance to FGFR inhibitors in FGFR1-driven leukemia/lymphomas.

Cowell JK, Qin H, Hu T, Wu Q, Bhole A, Ren M. Cowell JK, et al. Among authors: qin h. Int J Cancer. 2017 Nov 1;141(9):1822-1829. doi: 10.1002/ijc.30848. Epub 2017 Jul 28. Int J Cancer. 2017. PMID: 28646488 Free PMC article.

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