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Small molecule inhibitor regorafenib inhibits RET signaling in neuroblastoma cells and effectively suppresses tumor growth in vivo.
Chen Z, Zhao Y, Yu Y, Pang JC, Woodfield SE, Tao L, Guan S, Zhang H, Bieerkehazhi S, Shi Y, Patel R, Vasudevan SA, Yi JS, Muscal JA, Xu GT, Yang J. Chen Z, et al. Among authors: guan s. Oncotarget. 2017 Oct 24;8(61):104090-104103. doi: 10.18632/oncotarget.22011. eCollection 2017 Nov 28. Oncotarget. 2017. PMID: 29262623 Free PMC article.
MELK is a novel therapeutic target in high-risk neuroblastoma.
Guan S, Lu J, Zhao Y, Yu Y, Li H, Chen Z, Shi Z, Liang H, Wang M, Guo K, Chen X, Sun W, Bieerkehazhi S, Xu X, Sun S, Agarwal S, Yang J. Guan S, et al. Oncotarget. 2017 Dec 20;9(2):2591-2602. doi: 10.18632/oncotarget.23515. eCollection 2018 Jan 5. Oncotarget. 2017. PMID: 29416794 Free PMC article.
2,517 results