Stokes JM - Search Results

1

Overcoming mcr-1 mediated colistin resistance with colistin in combination with other antibiotics.

MacNair CR, Stokes JM, Carfrae LA, Fiebig-Comyn AA, Coombes BK, Mulvey MR, Brown ED. MacNair CR, et al. Among authors: stokes jm. Nat Commun. 2018 Jan 31;9(1):458. doi: 10.1038/s41467-018-02875-z. Nat Commun. 2018. PMID: 29386620 Free PMC article.

2

Discovery of a small molecule that inhibits bacterial ribosome biogenesis.

Stokes JM, Davis JH, Mangat CS, Williamson JR, Brown ED. Stokes JM, et al. Elife. 2014 Sep 18;3:e03574. doi: 10.7554/eLife.03574. Elife. 2014. PMID: 25233066 Free PMC article.

3

Chemical inhibition of bacterial ribosome biogenesis shows efficacy in a worm infection model.

Stokes JM, Selin C, Cardona ST, Brown ED. Stokes JM, et al. Antimicrob Agents Chemother. 2015 May;59(5):2918-20. doi: 10.1128/AAC.04690-14. Epub 2015 Feb 23. Antimicrob Agents Chemother. 2015. PMID: 25712357 Free PMC article.

4

Chemical modulators of ribosome biogenesis as biological probes.

Stokes JM, Brown ED. Stokes JM, et al. Nat Chem Biol. 2015 Dec;11(12):924-32. doi: 10.1038/nchembio.1957. Epub 2015 Nov 17. Nat Chem Biol. 2015. PMID: 26575239

5

Cold Stress Makes Escherichia coli Susceptible to Glycopeptide Antibiotics by Altering Outer Membrane Integrity.

Stokes JM, French S, Ovchinnikova OG, Bouwman C, Whitfield C, Brown ED. Stokes JM, et al. Cell Chem Biol. 2016 Feb 18;23(2):267-277. doi: 10.1016/j.chembiol.2015.12.011. Epub 2016 Feb 4. Cell Chem Biol. 2016. PMID: 26853624 Free article.

6

A cell-based approach to characterize antimicrobial compounds through kinetic dose response.

MacNair CR, Stokes JM, French S, Myers CL, Iyer KR, Brown ED. MacNair CR, et al. Among authors: stokes jm. Bioorg Med Chem. 2016 Dec 15;24(24):6315-6319. doi: 10.1016/j.bmc.2016.09.053. Epub 2016 Sep 22. Bioorg Med Chem. 2016. PMID: 27713016

7

Pentamidine sensitizes Gram-negative pathogens to antibiotics and overcomes acquired colistin resistance.

Stokes JM, MacNair CR, Ilyas B, French S, Côté JP, Bouwman C, Farha MA, Sieron AO, Whitfield C, Coombes BK, Brown ED. Stokes JM, et al. Nat Microbiol. 2017 Mar 6;2:17028. doi: 10.1038/nmicrobiol.2017.28. Nat Microbiol. 2017. PMID: 28263303 Free PMC article.

8

Bacteria Getting into Shape: Genetic Determinants of E. coli Morphology.

French S, Côté JP, Stokes JM, Truant R, Brown ED. French S, et al. Among authors: stokes jm. mBio. 2017 Mar 7;8(2):e01977-16. doi: 10.1128/mBio.01977-16. mBio. 2017. PMID: 28270582 Free PMC article.

9

Bicarbonate Alters Bacterial Susceptibility to Antibiotics by Targeting the Proton Motive Force.

Farha MA, French S, Stokes JM, Brown ED. Farha MA, et al. Among authors: stokes jm. ACS Infect Dis. 2018 Mar 9;4(3):382-390. doi: 10.1021/acsinfecdis.7b00194. Epub 2018 Jan 4. ACS Infect Dis. 2018. PMID: 29264917

10

A multiplexable assay for screening antibiotic lethality against drug-tolerant bacteria.

Stokes JM, Gutierrez A, Lopatkin AJ, Andrews IW, French S, Matic I, Brown ED, Collins JJ. Stokes JM, et al. Nat Methods. 2019 Apr;16(4):303-306. doi: 10.1038/s41592-019-0333-y. Epub 2019 Mar 11. Nat Methods. 2019. PMID: 30858599

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