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Cryo-EM structure of 5-HT3A receptor in its resting conformation.
Basak S, Gicheru Y, Samanta A, Molugu SK, Huang W, Fuente M, Hughes T, Taylor DJ, Nieman MT, Moiseenkova-Bell V, Chakrapani S. Basak S, et al. Among authors: chakrapani s. Nat Commun. 2018 Feb 6;9(1):514. doi: 10.1038/s41467-018-02997-4. Nat Commun. 2018. PMID: 29410406 Free PMC article.
Structural insight into the assembly of TRPV channels.
Huynh KW, Cohen MR, Chakrapani S, Holdaway HA, Stewart PL, Moiseenkova-Bell VY. Huynh KW, et al. Among authors: chakrapani s. Structure. 2014 Feb 4;22(2):260-8. doi: 10.1016/j.str.2013.11.008. Epub 2013 Dec 26. Structure. 2014. PMID: 24373766 Free PMC article.
Structural basis of TRPV5 channel inhibition by econazole revealed by cryo-EM.
Hughes TET, Lodowski DT, Huynh KW, Yazici A, Del Rosario J, Kapoor A, Basak S, Samanta A, Han X, Chakrapani S, Zhou ZH, Filizola M, Rohacs T, Han S, Moiseenkova-Bell VY. Hughes TET, et al. Among authors: chakrapani s. Nat Struct Mol Biol. 2018 Jan;25(1):53-60. doi: 10.1038/s41594-017-0009-1. Epub 2018 Jan 1. Nat Struct Mol Biol. 2018. PMID: 29323279 Free PMC article.
Direct visualization of ion-channel gating in a native environment.
Gicheru Y, Chakrapani S. Gicheru Y, et al. Among authors: chakrapani s. Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):10198-10200. doi: 10.1073/pnas.1814277115. Epub 2018 Sep 26. Proc Natl Acad Sci U S A. 2018. PMID: 30257939 Free PMC article. No abstract available.
70 results