Hayashi Y - Search Results

1

Development of a carboplatin derivative conjugated with a collagen-like triple-helical peptide.

Masuda R, Hayashi R, Nose H, Taguchi A, Hayashi Y, Yasui H, Koide T. Masuda R, et al. Among authors: hayashi y, hayashi r. Future Med Chem. 2018 Mar 1;10(6):619-629. doi: 10.4155/fmc-2017-0183. Epub 2018 Feb 7. Future Med Chem. 2018. PMID: 29412009

2

Development of water-soluble prodrugs of the HIV-1 protease inhibitor KNI-727: importance of the conversion time for higher gastrointestinal absorption of prodrugs based on spontaneous chemical cleavage.

Sohma Y, Hayashi Y, Ito T, Matsumoto H, Kimura T, Kiso Y. Sohma Y, et al. Among authors: hayashi y. J Med Chem. 2003 Sep 11;46(19):4124-35. doi: 10.1021/jm030009m. J Med Chem. 2003. PMID: 12954064

3

No auxiliary, no byproduct strategy for water-soluble prodrugs of taxoids: scope and limitation of O-N intramolecular acyl and acyloxy migration reactions.

Skwarczynski M, Sohma Y, Noguchi M, Kimura M, Hayashi Y, Hamada Y, Kimura T, Kiso Y. Skwarczynski M, et al. Among authors: hayashi y. J Med Chem. 2005 Apr 7;48(7):2655-66. doi: 10.1021/jm049344g. J Med Chem. 2005. PMID: 15801856

4

Development of first photoresponsive prodrug of paclitaxel.

Skwarczynski M, Noguchi M, Hirota S, Sohma Y, Kimura T, Hayashi Y, Kiso Y. Skwarczynski M, et al. Among authors: hayashi y. Bioorg Med Chem Lett. 2006 Sep 1;16(17):4492-6. doi: 10.1016/j.bmcl.2006.06.030. Epub 2006 Jun 27. Bioorg Med Chem Lett. 2006. PMID: 16806915

5

Paclitaxel prodrugs: toward smarter delivery of anticancer agents.

Skwarczynski M, Hayashi Y, Kiso Y. Skwarczynski M, et al. Among authors: hayashi y. J Med Chem. 2006 Dec 14;49(25):7253-69. doi: 10.1021/jm0602155. J Med Chem. 2006. PMID: 17149855 Review. No abstract available.

6

Tubulin photoaffinity labeling with biotin-tagged derivatives of potent diketopiperazine antimicrotubule agents.

Yamazaki Y, Kohno K, Yasui H, Kiso Y, Akamatsu M, Nicholson B, Deyanat-Yazdi G, Neuteboom S, Potts B, Lloyd GK, Hayashi Y. Yamazaki Y, et al. Among authors: hayashi y. Chembiochem. 2008 Dec 15;9(18):3074-81. doi: 10.1002/cbic.200800317. Chembiochem. 2008. PMID: 19012291

7

Synthesis of biotin-tagged diketopiperazine-based anti-microtubule agents and tubulin photoaffinity labeling.

Yamazaki Y, Kohno K, Yasui H, Kiso Y, Neuteboom S, Barral AM, Potts B, Lloyd GK, Hayashi Y. Yamazaki Y, et al. Among authors: hayashi y. Adv Exp Med Biol. 2009;611:527-8. doi: 10.1007/978-0-387-73657-0_230. Adv Exp Med Biol. 2009. PMID: 19400297 No abstract available.

8

Small-sized human immunodeficiency virus type-1 protease inhibitors containing allophenylnorstatine to explore the S2' pocket.

Hidaka K, Kimura T, Abdel-Rahman HM, Nguyen JT, McDaniel KF, Kohlbrenner WE, Molla A, Adachi M, Tamada T, Kuroki R, Katsuki N, Tanaka Y, Matsumoto H, Wang J, Hayashi Y, Kempf DJ, Kiso Y. Hidaka K, et al. Among authors: hayashi y. J Med Chem. 2009 Dec 10;52(23):7604-17. doi: 10.1021/jm9005115. J Med Chem. 2009. PMID: 19954246

9

Anti-microtubule 'plinabulin' chemical probe KPU-244-B3 labeled both alpha- and beta-tubulin.

Yamazaki Y, Sumikura M, Hidaka K, Yasui H, Kiso Y, Yakushiji F, Hayashi Y. Yamazaki Y, et al. Among authors: hayashi y. Bioorg Med Chem. 2010 May 1;18(9):3169-74. doi: 10.1016/j.bmc.2010.03.037. Epub 2010 Mar 23. Bioorg Med Chem. 2010. PMID: 20395148

10

Tubulin photoaffinity labeling study with a plinabulin chemical probe possessing a biotin tag at the oxazole.

Yamazaki Y, Kido Y, Hidaka K, Yasui H, Kiso Y, Yakushiji F, Hayashi Y. Yamazaki Y, et al. Among authors: hayashi y. Bioorg Med Chem. 2011 Jan 1;19(1):595-602. doi: 10.1016/j.bmc.2010.10.055. Epub 2010 Oct 31. Bioorg Med Chem. 2011. PMID: 21106379

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