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TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance.
Weber B, Schuster S, Zysset D, Rihs S, Dickgreber N, Schürch C, Riether C, Siegrist M, Schneider C, Pawelski H, Gurzeler U, Ziltener P, Genitsch V, Tacchini-Cottier F, Ochsenbein A, Hofstetter W, Kopf M, Kaufmann T, Oxenius A, Reith W, Saurer L, Mueller C. Weber B, et al. Among authors: genitsch v. PLoS Pathog. 2014 Jan;10(1):e1003900. doi: 10.1371/journal.ppat.1003900. Epub 2014 Jan 16. PLoS Pathog. 2014. PMID: 24453980 Free PMC article.
CD4 T cells are required for both development and maintenance of disease in a new mouse model of reversible colitis.
Brasseit J, Althaus-Steiner E, Faderl M, Dickgreber N, Saurer L, Genitsch V, Dolowschiak T, Li H, Finke D, Hardt WD, McCoy KD, Macpherson AJ, Corazza N, Noti M, Mueller C. Brasseit J, et al. Among authors: genitsch v. Mucosal Immunol. 2016 May;9(3):689-701. doi: 10.1038/mi.2015.93. Epub 2015 Sep 16. Mucosal Immunol. 2016. PMID: 26376366 Free article.
The ESRP1-GPR137 axis contributes to intestinal pathogenesis.
Mager LF, Koelzer VH, Stuber R, Thoo L, Keller I, Koeck I, Langenegger M, Simillion C, Pfister SP, Faderl M, Genitsch V, Tcymbarevich I, Juillerat P, Li X, Xia Y, Karamitopoulou E, Lyck R, Zlobec I, Hapfelmeier S, Bruggmann R, McCoy KD, Macpherson AJ, Müller C, Beutler B, Krebs P. Mager LF, et al. Among authors: genitsch v. Elife. 2017 Oct 4;6:e28366. doi: 10.7554/eLife.28366. Elife. 2017. PMID: 28975893 Free PMC article.
The IL-33/ST2 pathway contributes to intestinal tumorigenesis in humans and mice.
Mertz KD, Mager LF, Wasmer MH, Thiesler T, Koelzer VH, Ruzzante G, Joller S, Murdoch JR, Brümmendorf T, Genitsch V, Lugli A, Cathomas G, Moch H, Weber A, Zlobec I, Junt T, Krebs P. Mertz KD, et al. Among authors: genitsch v. Oncoimmunology. 2015 Jun 26;5(1):e1062966. doi: 10.1080/2162402X.2015.1062966. eCollection 2016. Oncoimmunology. 2015. PMID: 26942077 Free PMC article.
35 results