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Astrocyte-derived interleukin-33 promotes microglial synapse engulfment and neural circuit development.
Vainchtein ID, Chin G, Cho FS, Kelley KW, Miller JG, Chien EC, Liddelow SA, Nguyen PT, Nakao-Inoue H, Dorman LC, Akil O, Joshita S, Barres BA, Paz JT, Molofsky AB, Molofsky AV. Vainchtein ID, et al. Among authors: paz jt. Science. 2018 Mar 16;359(6381):1269-1273. doi: 10.1126/science.aal3589. Epub 2018 Feb 1. Science. 2018. PMID: 29420261 Free PMC article.
Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation.
Lui H, Zhang J, Makinson SR, Cahill MK, Kelley KW, Huang HY, Shang Y, Oldham MC, Martens LH, Gao F, Coppola G, Sloan SA, Hsieh CL, Kim CC, Bigio EH, Weintraub S, Mesulam MM, Rademakers R, Mackenzie IR, Seeley WW, Karydas A, Miller BL, Borroni B, Ghidoni R, Farese RV Jr, Paz JT, Barres BA, Huang EJ. Lui H, et al. Among authors: paz jt. Cell. 2016 May 5;165(4):921-35. doi: 10.1016/j.cell.2016.04.001. Epub 2016 Apr 21. Cell. 2016. PMID: 27114033 Free PMC article.
Augmented Reticular Thalamic Bursting and Seizures in Scn1a-Dravet Syndrome.
Ritter-Makinson S, Clemente-Perez A, Higashikubo B, Cho FS, Holden SS, Bennett E, Chkhaidze A, Eelkman Rooda OHJ, Cornet MC, Hoebeek FE, Yamakawa K, Cilio MR, Delord B, Paz JT. Ritter-Makinson S, et al. Among authors: paz jt. Cell Rep. 2019 Jan 2;26(1):54-64.e6. doi: 10.1016/j.celrep.2018.12.018. Cell Rep. 2019. PMID: 30605686 Free PMC article.
Complement factor C1q mediates sleep spindle loss and epileptic spikes after mild brain injury.
Holden SS, Grandi FC, Aboubakr O, Higashikubo B, Cho FS, Chang AH, Forero AO, Morningstar AR, Mathur V, Kuhn LJ, Suri P, Sankaranarayanan S, Andrews-Zwilling Y, Tenner AJ, Luthi A, Aronica E, Corces MR, Yednock T, Paz JT. Holden SS, et al. Among authors: paz jt. Science. 2021 Sep 10;373(6560):eabj2685. doi: 10.1126/science.abj2685. Epub 2021 Sep 10. Science. 2021. PMID: 34516796 Free PMC article.
Enhancing GAT-3 in thalamic astrocytes promotes resilience to brain injury in rodents.
Cho FS, Vainchtein ID, Voskobiynyk Y, Morningstar AR, Aparicio F, Higashikubo B, Ciesielska A, Broekaart DWM, Anink JJ, van Vliet EA, Yu X, Khakh BS, Aronica E, Molofsky AV, Paz JT. Cho FS, et al. Among authors: paz jt. Sci Transl Med. 2022 Jul 6;14(652):eabj4310. doi: 10.1126/scitranslmed.abj4310. Epub 2022 Jul 6. Sci Transl Med. 2022. PMID: 35857628 Free PMC article.
41 results