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A de novo Ser111Thr variant in aquaporin-4 in a patient with intellectual disability, transient signs of brain ischemia, transient cardiac hypertrophy, and progressive gait disturbance.
Berland S, Toft-Bertelsen TL, Aukrust I, Byska J, Vaudel M, Bindoff LA, MacAulay N, Houge G. Berland S, et al. Cold Spring Harb Mol Case Stud. 2018 Feb 1;4(1):a002303. doi: 10.1101/mcs.a002303. Print 2018 Feb. Cold Spring Harb Mol Case Stud. 2018. PMID: 29437797 Free PMC article.
Evaluating the involvement of cerebral microvascular endothelial Na+/K+-ATPase and Na+-K+-2Cl- co-transporter in electrolyte fluxes in an in vitro blood-brain barrier model of dehydration.
Lykke K, Assentoft M, Hørlyck S, Helms HC, Stoica A, Toft-Bertelsen TL, Tritsaris K, Vilhardt F, Brodin B, MacAulay N. Lykke K, et al. J Cereb Blood Flow Metab. 2019 Mar;39(3):497-512. doi: 10.1177/0271678X17736715. Epub 2017 Oct 10. J Cereb Blood Flow Metab. 2019. PMID: 28994331 Free PMC article.
Bumepamine, a brain-permeant benzylamine derivative of bumetanide, does not inhibit NKCC1 but is more potent to enhance phenobarbital's anti-seizure efficacy.
Brandt C, Seja P, Töllner K, Römermann K, Hampel P, Kalesse M, Kipper A, Feit PW, Lykke K, Toft-Bertelsen TL, Paavilainen P, Spoljaric I, Puskarjov M, MacAulay N, Kaila K, Löscher W. Brandt C, et al. Neuropharmacology. 2018 Dec;143:186-204. doi: 10.1016/j.neuropharm.2018.09.025. Epub 2018 Sep 21. Neuropharmacology. 2018. PMID: 30248303
Corrigendum to "Bumepamine, a brain-permeant benzylamine derivative of bumetanide, does not inhibit NKCC1 but is more potent to enhance phenobarbital's antiseizure efficacy" [Neuropharmacology 143 (2018) 186-204].
Brandt C, Seja P, Töllner K, Römermann K, Hampel P, Kalesse M, Kipper A, Feit PW, Lykke K, Toft-Bertelsen TL, Paavilainen P, Spoljaric I, Puskarjov M, MacAulay N, Kaila K, Löscher W. Brandt C, et al. Neuropharmacology. 2018 Dec;143:349-350. doi: 10.1016/j.neuropharm.2018.10.012. Epub 2018 Oct 19. Neuropharmacology. 2018. PMID: 30343990 No abstract available.
Pannexin 1 activation and inhibition is permeant-selective.
Nielsen BS, Toft-Bertelsen TL, Lolansen SD, Anderson CL, Nielsen MS, Thompson RJ, MacAulay N. Nielsen BS, et al. J Physiol. 2020 Jan;598(2):361-379. doi: 10.1113/JP278759. Epub 2020 Jan 6. J Physiol. 2020. PMID: 31698505 Free article.
34 results