CD95/Fas ligand mRNA is toxic to cells.
Putzbach W, Haluck-Kangas A, Gao QQ, Sarshad AA, Bartom ET, Stults A, Qadir AS, Hafner M, Peter ME.
Putzbach W, et al.
Elife. 2018 Oct 16;7:e38621. doi: 10.7554/eLife.38621.
Elife. 2018.
PMID: 30324908
Free PMC article.
CD95/Fas ligand binds to the death receptor CD95 to induce apoptosis in sensitive cells. We previously reported that CD95L mRNA is enriched in sequences that, when converted to si/shRNAs, kill all cancer cells by targeting critical survival genes (Putzbach et al., 2 …
CD95/Fas ligand binds to the death receptor CD95 to induce apoptosis in sensitive cells. We previously reported that CD95L mRNA is en …