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Mitochondria as pharmacological targets in Down syndrome.
Valenti D, Braidy N, De Rasmo D, Signorile A, Rossi L, Atanasov AG, Volpicella M, Henrion-Caude A, Nabavi SM, Vacca RA. Valenti D, et al. Among authors: vacca ra. Free Radic Biol Med. 2018 Jan;114:69-83. doi: 10.1016/j.freeradbiomed.2017.08.014. Epub 2017 Aug 31. Free Radic Biol Med. 2018. PMID: 28838841 Review.
Inhibition of Drp1-mediated mitochondrial fission improves mitochondrial dynamics and bioenergetics stimulating neurogenesis in hippocampal progenitor cells from a Down syndrome mouse model.
Valenti D, Rossi L, Marzulli D, Bellomo F, De Rasmo D, Signorile A, Vacca RA. Valenti D, et al. Among authors: vacca ra. Biochim Biophys Acta Mol Basis Dis. 2017 Dec;1863(12):3117-3127. doi: 10.1016/j.bbadis.2017.09.014. Epub 2017 Sep 20. Biochim Biophys Acta Mol Basis Dis. 2017. PMID: 28939434 Free article.
Down syndrome: Neurobiological alterations and therapeutic targets.
Vacca RA, Bawari S, Valenti D, Tewari D, Nabavi SF, Shirooie S, Sah AN, Volpicella M, Braidy N, Nabavi SM. Vacca RA, et al. Neurosci Biobehav Rev. 2019 Mar;98:234-255. doi: 10.1016/j.neubiorev.2019.01.001. Epub 2019 Jan 4. Neurosci Biobehav Rev. 2019. PMID: 30615933 Review.
Epigallocatechin-3-Gallate Plus Omega-3 Restores the Mitochondrial Complex I and F0F1-ATP Synthase Activities in PBMCs of Young Children with Down Syndrome: A Pilot Study of Safety and Efficacy.
Scala I, Valenti D, Scotto D'Aniello V, Marino M, Riccio MP, Bravaccio C, Vacca RA, Strisciuglio P. Scala I, et al. Among authors: vacca ra. Antioxidants (Basel). 2021 Mar 16;10(3):469. doi: 10.3390/antiox10030469. Antioxidants (Basel). 2021. PMID: 33809669 Free PMC article.
68 results