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Synthesis of Novel Tetrahydroisoquinoline CXCR4 Antagonists with Rigidified Side-Chains.
Jecs E, Miller EJ, Wilson RJ, Nguyen HH, Tahirovic YA, Katzman BM, Truax VM, Kim MB, Kuo KM, Wang T, Sum CS, Cvijic ME, Schroeder GM, Wilson LJ, Liotta DC. Jecs E, et al. Among authors: liotta dc. ACS Med Chem Lett. 2017 Dec 20;9(2):89-93. doi: 10.1021/acsmedchemlett.7b00406. eCollection 2018 Feb 8. ACS Med Chem Lett. 2017. PMID: 29456793 Free PMC article.
Discovery of small molecule CXCR4 antagonists.
Zhan W, Liang Z, Zhu A, Kurtkaya S, Shim H, Snyder JP, Liotta DC. Zhan W, et al. Among authors: liotta dc. J Med Chem. 2007 Nov 15;50(23):5655-64. doi: 10.1021/jm070679i. Epub 2007 Oct 24. J Med Chem. 2007. PMID: 17958344
Enantiomeric propanolamines as selective N-methyl-D-aspartate 2B receptor antagonists.
Tahirovic YA, Geballe M, Gruszecka-Kowalik E, Myers SJ, Lyuboslavsky P, Le P, French A, Irier H, Choi WB, Easterling K, Yuan H, Wilson LJ, Kotloski R, McNamara JO, Dingledine R, Liotta DC, Traynelis SF, Snyder JP. Tahirovic YA, et al. Among authors: liotta dc. J Med Chem. 2008 Sep 25;51(18):5506-21. doi: 10.1021/jm8002153. J Med Chem. 2008. PMID: 18800760 Free PMC article.
Synthesis, structural activity-relationships, and biological evaluation of novel amide-based allosteric binding site antagonists in NR1A/NR2B N-methyl-D-aspartate receptors.
Mosley CA, Myers SJ, Murray EE, Santangelo R, Tahirovic YA, Kurtkaya N, Mullasseril P, Yuan H, Lyuboslavsky P, Le P, Wilson LJ, Yepes M, Dingledine R, Traynelis SF, Liotta DC. Mosley CA, et al. Among authors: liotta dc. Bioorg Med Chem. 2009 Sep 1;17(17):6463-80. doi: 10.1016/j.bmc.2009.05.085. Epub 2009 Jul 5. Bioorg Med Chem. 2009. PMID: 19648014 Free PMC article.
293 results