Garcia-Manero G - Search Results

1

Genetic rescue of lineage-balanced blood cell production reveals a crucial role for STAT3 antiinflammatory activity in hematopoiesis.

Zhang H, Li HS, Hillmer EJ, Zhao Y, Chrisikos TT, Hu H, Wu X, Thompson EJ, Clise-Dwyer K, Millerchip KA, Wei Y, Puebla-Osorio N, Kaushik S, Santos MA, Wang B, Garcia-Manero G, Wang J, Sun SC, Watowich SS. Zhang H, et al. Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):E2311-E2319. doi: 10.1073/pnas.1713889115. Epub 2018 Feb 20. Proc Natl Acad Sci U S A. 2018. PMID: 29463696 Free PMC article.

2

Preclinical antileukemia activity of JNJ-26481585, a potent second-generation histone deacetylase inhibitor.

Tong WG, Wei Y, Stevenson W, Kuang SQ, Fang Z, Zhang M, Arts J, Garcia-Manero G. Tong WG, et al. Leuk Res. 2010 Feb;34(2):221-8. doi: 10.1016/j.leukres.2009.07.024. Epub 2009 Aug 13. Leuk Res. 2010. PMID: 19682743

3

Genome-wide DNA methylation profiling of chronic lymphocytic leukemia allows identification of epigenetically repressed molecular pathways with clinical impact.

Tong WG, Wierda WG, Lin E, Kuang SQ, Bekele BN, Estrov Z, Wei Y, Yang H, Keating MJ, Garcia-Manero G. Tong WG, et al. Epigenetics. 2010 Aug 16;5(6):499-508. doi: 10.4161/epi.5.6.12179. Epub 2010 Aug 16. Epigenetics. 2010. PMID: 20484983 Free PMC article.

4

The combination of a histone deacetylase inhibitor with the Bcl-2 homology domain-3 mimetic GX15-070 has synergistic antileukemia activity by activating both apoptosis and autophagy.

Wei Y, Kadia T, Tong W, Zhang M, Jia Y, Yang H, Hu Y, Tambaro FP, Viallet J, O'Brien S, Garcia-Manero G. Wei Y, et al. Clin Cancer Res. 2010 Aug 1;16(15):3923-32. doi: 10.1158/1078-0432.CCR-10-0032. Epub 2010 Jun 10. Clin Cancer Res. 2010. PMID: 20538760 Free PMC article.

5

Overcoming resistance to histone deacetylase inhibitors in human leukemia with the redox modulating compound β-phenylethyl isothiocyanate.

Hu Y, Lu W, Chen G, Zhang H, Jia Y, Wei Y, Yang H, Zhang W, Fiskus W, Bhalla K, Keating M, Huang P, Garcia-Manero G. Hu Y, et al. Blood. 2010 Oct 14;116(15):2732-41. doi: 10.1182/blood-2009-11-256354. Epub 2010 Jun 21. Blood. 2010. PMID: 20566897 Free PMC article.

6

The combination of a histone deacetylase inhibitor with the BH3-mimetic GX15-070 has synergistic antileukemia activity by activating both apoptosis and autophagy.

Wei Y, Kadia T, Tong W, Zhang M, Jia Y, Yang H, Hu Y, Viallet J, O'Brien S, Garcia-Manero G. Wei Y, et al. Autophagy. 2010 Oct;6(7):976-8. doi: 10.4161/auto.6.7.13117. Epub 2010 Oct 23. Autophagy. 2010. PMID: 20729640

7

Histone methylation in myelodysplastic syndromes.

Wei Y, Gañán-Gómez I, Salazar-Dimicoli S, McCay SL, Garcia-Manero G. Wei Y, et al. Epigenomics. 2011 Apr;3(2):193-205. doi: 10.2217/epi.11.9. Epigenomics. 2011. PMID: 22122281 Free PMC article. Review.

8

Epigenetic inactivation of Notch-Hes pathway in human B-cell acute lymphoblastic leukemia.

Kuang SQ, Fang Z, Zweidler-McKay PA, Yang H, Wei Y, Gonzalez-Cervantes EA, Boumber Y, Garcia-Manero G. Kuang SQ, et al. PLoS One. 2013 Apr 26;8(4):e61807. doi: 10.1371/journal.pone.0061807. Print 2013. PLoS One. 2013. PMID: 23637910 Free PMC article.

9

Impact of aberrant DNA methylation patterns including CYP1B1 methylation in adolescents and young adults with acute lymphocytic leukemia.

DiNardo CD, Gharibyan V, Yang H, Wei Y, Pierce S, Kantarjian HM, Garcia-Manero G, Rytting M. DiNardo CD, et al. Am J Hematol. 2013 Sep;88(9):784-9. doi: 10.1002/ajh.23511. Epub 2013 Jul 23. Am J Hematol. 2013. PMID: 23757320 Free PMC article.

10

Acquisition of cytogenetic abnormalities in patients with IPSS defined lower-risk myelodysplastic syndrome is associated with poor prognosis and transformation to acute myelogenous leukemia.

Jabbour E, Takahashi K, Wang X, Cornelison AM, Abruzzo L, Kadia T, Borthakur G, Estrov Z, O'Brien S, Mallo M, Wierda W, Pierce S, Wei Y, Sole F, Chen R, Kantarjian H, Garcia-Manero G. Jabbour E, et al. Am J Hematol. 2013 Oct;88(10):831-7. doi: 10.1002/ajh.23513. Epub 2013 Jul 23. Am J Hematol. 2013. PMID: 23760779 Free PMC article. Clinical Trial.

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