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PARP inhibitors in platinum-sensitive high-grade serous ovarian cancer.
Morgan RD, Clamp AR, Evans DGR, Edmondson RJ, Jayson GC. Morgan RD, et al. Among authors: evans dgr. Cancer Chemother Pharmacol. 2018 Apr;81(4):647-658. doi: 10.1007/s00280-018-3532-9. Epub 2018 Feb 20. Cancer Chemother Pharmacol. 2018. PMID: 29464354 Free PMC article. Review.
Mainstreaming germline BRCA1/2 testing in non-mucinous epithelial ovarian cancer in the North West of England.
Flaum N, Morgan RD, Burghel GJ, Bulman M, Clamp AR, Hasan J, Mitchell CL, Badea D, Moon S, Hogg M, Hadjiyiannakis D, Clancy T, Schlecht H, Woodward ER, Crosbie EJ, Edmondson RJ, Wallace AJ, Jayson GC, Lalloo FI, Harkness EF, Evans DGR. Flaum N, et al. Among authors: evans dgr. Eur J Hum Genet. 2020 Nov;28(11):1541-1547. doi: 10.1038/s41431-020-0692-y. Epub 2020 Jul 10. Eur J Hum Genet. 2020. PMID: 32651552 Free PMC article.
BRCA1/2 in non-mucinous epithelial ovarian cancer: tumour with or without germline testing?
Morgan RD, Burghel GJ, Flaum N, Bulman M, Smith P, Clamp AR, Hasan J, Mitchell CL, Salih Z, Woodward ER, Lalloo F, Crosbie EJ, Edmondson RJ, Wallace AJ, Jayson GC, Evans DGR. Morgan RD, et al. Among authors: evans dgr. Br J Cancer. 2022 Jul;127(1):163-167. doi: 10.1038/s41416-022-01773-y. Epub 2022 Mar 8. Br J Cancer. 2022. PMID: 35260807 Free PMC article. Review.
Predicting the likelihood of a BRCA1/2 pathogenic variant being somatic by testing only tumour DNA in non-mucinous high-grade epithelial ovarian cancer.
Morgan RD, Burghel GJ, Flaum N, Bulman M, Smith P, Clamp AR, Hasan J, Mitchell C, Salih Z, Woodward ER, Lalloo F, Shaw J, Desai S, Crosbie EJ, Edmondson RJ, Schlecht H, Wallace AJ, Jayson GC, Evans DGR. Morgan RD, et al. Among authors: evans dgr. J Clin Pathol. 2023 Oct;76(10):684-689. doi: 10.1136/jcp-2022-208369. Epub 2022 Jun 23. J Clin Pathol. 2023. PMID: 35738887
Is Reflex Germline BRCA1/2 Testing Necessary in Women Diagnosed with Non-Mucinous High-Grade Epithelial Ovarian Cancer Aged 80 Years or Older?
Morgan RD, Burghel GJ, Flaum N, Bulman M, Smith P, Clamp AR, Hasan J, Mitchell CL, Salih Z, Woodward ER, Lalloo F, Crosbie EJ, Edmondson RJ, Schlecht H, Jayson GC, Evans DGR. Morgan RD, et al. Among authors: evans dgr. Cancers (Basel). 2023 Jan 25;15(3):730. doi: 10.3390/cancers15030730. Cancers (Basel). 2023. PMID: 36765687 Free PMC article.
Multi-Maintenance Olaparib Therapy in Relapsed, Germline BRCA1/2-Mutant High-Grade Serous Ovarian Cancer (MOLTO): A Phase II Trial.
Morgan RD, Clamp AR, White DJ, Price M, Burghel GJ, Ryder WDJ, Mahmood RD, Murphy AD, Hasan J, Mitchell CL, Salih Z, Wheeler C, Buckley E, Truelove J, King G, Ainaoui Y, Bhaskar SS, Shaw J, Evans DGR, Kilerci B, Pearce SP, Brady G, Dive C, O'Connor JPB, Wallace AJ, Rothwell DG, Edmondson RJ, Jayson GC. Morgan RD, et al. Among authors: evans dgr. Clin Cancer Res. 2023 Jul 14;29(14):2602-2611. doi: 10.1158/1078-0432.CCR-22-3282. Clin Cancer Res. 2023. PMID: 36799931
Extended panel testing in ovarian cancer reveals BRIP1 as the third most important predisposition gene.
Morgan RD, Burghel GJ, Flaum N, Schlecht H, Clamp AR, Hasan J, Mitchell C, Salih Z, Moon S, Hogg M, Lord R, Forde C, Lalloo F, Woodward ER, Crosbie EJ, Taylor SS, Jayson GC, Evans DGR. Morgan RD, et al. Among authors: evans dgr. Genet Med. 2024 Oct;26(10):101230. doi: 10.1016/j.gim.2024.101230. Epub 2024 Jul 31. Genet Med. 2024. PMID: 39096152 Free article.
Germline BRCA1/2 status and chemotherapy response score in high-grade serous ovarian cancer.
Morgan RD, Wang X, Barnes BM, Spurgeon L, Carrot A, Netto D, Hasan J, Mitchell C, Salih Z, Desai S, Shaw J, Winter-Roach B, Schlecht H, Burghel GJ, Clamp AR, Edmondson RJ, You B, Evans DGR, Jayson GC, Taylor SS. Morgan RD, et al. Among authors: evans dgr. Br J Cancer. 2024 Dec;131(12):1919-1927. doi: 10.1038/s41416-024-02874-6. Epub 2024 Nov 16. Br J Cancer. 2024. PMID: 39550490 Free PMC article.
175 results