Loos AH - Search Results

1

Safety profile of avelumab in patients with advanced solid tumors: A pooled analysis of data from the phase 1 JAVELIN solid tumor and phase 2 JAVELIN Merkel 200 clinical trials.

Kelly K, Infante JR, Taylor MH, Patel MR, Wong DJ, Iannotti N, Mehnert JM, Loos AH, Koch H, Speit I, Gulley JL. Kelly K, et al. Among authors: loos ah. Cancer. 2018 May 1;124(9):2010-2017. doi: 10.1002/cncr.31293. Epub 2018 Feb 22. Cancer. 2018. PMID: 29469949 Free PMC article.

2

Evaluation of the potential for QTc prolongation with avelumab.

Vugmeyster Y, Güzel G, Hennessy M, Loos AH, Dai H. Vugmeyster Y, et al. Among authors: loos ah. Cancer Chemother Pharmacol. 2019 Nov;84(5):1017-1026. doi: 10.1007/s00280-019-03925-z. Epub 2019 Sep 3. Cancer Chemother Pharmacol. 2019. PMID: 31478078 Free PMC article.

3

Model-informed approach for risk management of bleeding toxicities for bintrafusp alfa, a bifunctional fusion protein targeting TGF-β and PD-L1.

Vugmeyster Y, Grisic AM, Wilkins JJ, Loos AH, Hallwachs R, Osada M, Venkatakrishnan K, Khandelwal A. Vugmeyster Y, et al. Among authors: loos ah. Cancer Chemother Pharmacol. 2022 Oct;90(4):369-379. doi: 10.1007/s00280-022-04468-6. Epub 2022 Sep 6. Cancer Chemother Pharmacol. 2022. PMID: 36066618 Free PMC article.

4

Reduced incidence of infusion-related reactions in metastatic colorectal cancer during treatment with cetuximab plus irinotecan with combined corticosteroid and antihistamine premedication.

Siena S, Glynne-Jones R, Adenis A, Thaler J, Preusser P, Aguilar EA, Aapro MS, Loos AH, Esser R, Wilke H. Siena S, et al. Among authors: loos ah. Cancer. 2010 Apr 1;116(7):1827-37. doi: 10.1002/cncr.24945. Cancer. 2010. PMID: 20143444 Free article.

5

Multistate modeling of clinical hold in randomized clinical trials.

Nießl A, Beyersmann J, Loos A. Nießl A, et al. Pharm Stat. 2020 May;19(3):262-275. doi: 10.1002/pst.1989. Epub 2019 Dec 10. Pharm Stat. 2020. PMID: 31820541

6

Survival analysis for AdVerse events with VarYing follow-up times (SAVVY)-estimation of adverse event risks.

Stegherr R, Schmoor C, Beyersmann J, Rufibach K, Jehl V, Brückner A, Eisele L, Künzel T, Kupas K, Langer F, Leverkus F, Loos A, Norenberg C, Voss F, Friede T. Stegherr R, et al. Trials. 2021 Jun 29;22(1):420. doi: 10.1186/s13063-021-05354-x. Trials. 2021. PMID: 34187527 Free PMC article.

7

On estimands and the analysis of adverse events in the presence of varying follow-up times within the benefit assessment of therapies.

Unkel S, Amiri M, Benda N, Beyersmann J, Knoerzer D, Kupas K, Langer F, Leverkus F, Loos A, Ose C, Proctor T, Schmoor C, Schwenke C, Skipka G, Unnebrink K, Voss F, Friede T. Unkel S, et al. Pharm Stat. 2019 Mar;18(2):166-183. doi: 10.1002/pst.1915. Epub 2018 Nov 20. Pharm Stat. 2019. PMID: 30458579 Free PMC article.

8

Cetuximab plus irinotecan in heavily pretreated metastatic colorectal cancer progressing on irinotecan: MABEL Study.

Wilke H, Glynne-Jones R, Thaler J, Adenis A, Preusser P, Aguilar EA, Aapro MS, Esser R, Loos AH, Siena S. Wilke H, et al. Among authors: loos ah. J Clin Oncol. 2008 Nov 20;26(33):5335-43. doi: 10.1200/JCO.2008.16.3758. Epub 2008 Oct 14. J Clin Oncol. 2008. PMID: 18854570

9

Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer.

Bokemeyer C, Bondarenko I, Makhson A, Hartmann JT, Aparicio J, de Braud F, Donea S, Ludwig H, Schuch G, Stroh C, Loos AH, Zubel A, Koralewski P. Bokemeyer C, et al. Among authors: loos ah. J Clin Oncol. 2009 Feb 10;27(5):663-71. doi: 10.1200/JCO.2008.20.8397. Epub 2008 Dec 29. J Clin Oncol. 2009. PMID: 19114683 Free article. Clinical Trial.

10

Cetuximab in combination with irinotecan/5-fluorouracil/folinic acid (FOLFIRI) in the initial treatment of metastatic colorectal cancer: a multicentre two-part phase I/II study.

Raoul JL, Van Laethem JL, Peeters M, Brezault C, Husseini F, Cals L, Nippgen J, Loos AH, Rougier P. Raoul JL, et al. Among authors: loos ah. BMC Cancer. 2009 Apr 14;9:112. doi: 10.1186/1471-2407-9-112. BMC Cancer. 2009. PMID: 19366444 Free PMC article. Clinical Trial.

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