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Electron Cryo-microscopy Structure of Ebola Virus Nucleoprotein Reveals a Mechanism for Nucleocapsid-like Assembly.
Su Z, Wu C, Shi L, Luthra P, Pintilie GD, Johnson B, Porter JR, Ge P, Chen M, Liu G, Frederick TE, Binning JM, Bowman GR, Zhou ZH, Basler CF, Gross ML, Leung DW, Chiu W, Amarasinghe GK. Su Z, et al. Among authors: frederick te. Cell. 2018 Feb 22;172(5):966-978.e12. doi: 10.1016/j.cell.2018.02.009. Cell. 2018. PMID: 29474922 Free PMC article.
The Cap-Snatching SFTSV Endonuclease Domain Is an Antiviral Target.
Wang W, Shin WJ, Zhang B, Choi Y, Yoo JS, Zimmerman MI, Frederick TE, Bowman GR, Gross ML, Leung DW, Jung JU, Amarasinghe GK. Wang W, et al. Among authors: frederick te. Cell Rep. 2020 Jan 7;30(1):153-163.e5. doi: 10.1016/j.celrep.2019.12.020. Cell Rep. 2020. PMID: 31914382 Free PMC article.
A cryptic pocket in Ebola VP35 allosterically controls RNA binding.
Cruz MA, Frederick TE, Mallimadugula UL, Singh S, Vithani N, Zimmerman MI, Porter JR, Moeder KE, Amarasinghe GK, Bowman GR. Cruz MA, et al. Among authors: frederick te. Nat Commun. 2022 Apr 27;13(1):2269. doi: 10.1038/s41467-022-29927-9. Nat Commun. 2022. PMID: 35477718 Free PMC article.
Opening of a cryptic pocket in β-lactamase increases penicillinase activity.
Knoverek CR, Mallimadugula UL, Singh S, Rennella E, Frederick TE, Yuwen T, Raavicharla S, Kay LE, Bowman GR. Knoverek CR, et al. Among authors: frederick te. Proc Natl Acad Sci U S A. 2021 Nov 23;118(47):e2106473118. doi: 10.1073/pnas.2106473118. Proc Natl Acad Sci U S A. 2021. PMID: 34799442 Free PMC article.
Endogenous retinoid X receptor ligands in mouse hematopoietic cells.
Niu H, Fujiwara H, di Martino O, Hadwiger G, Frederick TE, Menéndez-Gutiérrez MP, Ricote M, Bowman GR, Welch JS. Niu H, et al. Among authors: frederick te. Sci Signal. 2017 Oct 31;10(503):eaan1011. doi: 10.1126/scisignal.aan1011. Sci Signal. 2017. PMID: 29089448 Free PMC article.
Repurposing Hsp90 inhibitors as antibiotics targeting histidine kinases.
Vo CD, Shebert HL, Zikovich S, Dryer RA, Huang TP, Moran LJ, Cho J, Wassarman DR, Falahee BE, Young PD, Gu GH, Heinl JF, Hammond JW, Jackvony TN, Frederick TE, Blair JA. Vo CD, et al. Among authors: frederick te. Bioorg Med Chem Lett. 2017 Dec 1;27(23):5235-5244. doi: 10.1016/j.bmcl.2017.10.036. Epub 2017 Oct 19. Bioorg Med Chem Lett. 2017. PMID: 29110989 Free article.
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