Baumann U - Search Results

1

A family of unconventional deubiquitinases with modular chain specificity determinants.

Hermanns T, Pichlo C, Woiwode I, Klopffleisch K, Witting KF, Ovaa H, Baumann U, Hofmann K. Hermanns T, et al. Among authors: baumann u. Nat Commun. 2018 Feb 23;9(1):799. doi: 10.1038/s41467-018-03148-5. Nat Commun. 2018. PMID: 29476094 Free PMC article.

2

Structural Basis of Proline-Proline Peptide Bond Specificity of the Metalloprotease Zmp1 Implicated in Motility of Clostridium difficile.

Schacherl M, Pichlo C, Neundorf I, Baumann U. Schacherl M, et al. Among authors: baumann u. Structure. 2015 Sep 1;23(9):1632-1642. doi: 10.1016/j.str.2015.06.018. Epub 2015 Jul 23. Structure. 2015. PMID: 26211609 Free article.

3

Production, Crystallization and Structure Determination of C. difficile PPEP-1 via Microseeding and Zinc-SAD.

Pichlo C, Montada AA, Schacherl M, Baumann U. Pichlo C, et al. Among authors: baumann u. J Vis Exp. 2016 Dec 30;(118):55022. doi: 10.3791/55022. J Vis Exp. 2016. PMID: 28060332 Free PMC article.

4

Optimized 4,5-Diarylimidazoles as Potent/Selective Inhibitors of Protein Kinase CK1δ and Their Structural Relation to p38α MAPK.

Halekotte J, Witt L, Ianes C, Krüger M, Bührmann M, Rauh D, Pichlo C, Brunstein E, Luxenburger A, Baumann U, Knippschild U, Bischof J, Peifer C. Halekotte J, et al. Among authors: baumann u. Molecules. 2017 Mar 24;22(4):522. doi: 10.3390/molecules22040522. Molecules. 2017. PMID: 28338621 Free PMC article.

5

Discovery of Inhibitor of Wnt Production 2 (IWP-2) and Related Compounds As Selective ATP-Competitive Inhibitors of Casein Kinase 1 (CK1) δ/ε.

García-Reyes B, Witt L, Jansen B, Karasu E, Gehring T, Leban J, Henne-Bruns D, Pichlo C, Brunstein E, Baumann U, Wesseler F, Rathmer B, Schade D, Peifer C, Knippschild U. García-Reyes B, et al. Among authors: baumann u. J Med Chem. 2018 May 10;61(9):4087-4102. doi: 10.1021/acs.jmedchem.8b00095. Epub 2018 May 1. J Med Chem. 2018. PMID: 29630366

6

Improved protein-crystal identification by using 2,2,2-trichloroethanol as a fluorescence enhancer.

Pichlo C, Toelzer C, Chojnacki K, Öcal S, Uthoff M, Ruegenberg S, Hermanns T, Schacherl M, Denzel MS, Hofmann K, Niefind K, Baumann U. Pichlo C, et al. Among authors: baumann u. Acta Crystallogr F Struct Biol Commun. 2018 May 1;74(Pt 5):307-314. doi: 10.1107/S2053230X18005253. Epub 2018 Apr 24. Acta Crystallogr F Struct Biol Commun. 2018. PMID: 29717999 Free PMC article.

7

Heterologous expression and characterization of a novel serine protease from Daphnia magna: A possible role in susceptibility to toxic cyanobacteria.

Lange J, Demir F, Huesgen PF, Baumann U, von Elert E, Pichlo C. Lange J, et al. Among authors: baumann u. Aquat Toxicol. 2018 Dec;205:140-147. doi: 10.1016/j.aquatox.2018.09.013. Epub 2018 Sep 26. Aquat Toxicol. 2018. PMID: 30384195

8

Design, Synthesis and Biological Evaluation of Isoxazole-Based CK1 Inhibitors Modified with Chiral Pyrrolidine Scaffolds.

Luxenburger A, Schmidt D, Ianes C, Pichlo C, Krüger M, von Drathen T, Brunstein E, Gainsford GJ, Baumann U, Knippschild U, Peifer C. Luxenburger A, et al. Among authors: baumann u. Molecules. 2019 Mar 1;24(5):873. doi: 10.3390/molecules24050873. Molecules. 2019. PMID: 30832206 Free PMC article.

9

Molecular determinants of the mechanism and substrate specificity of Clostridium difficile proline-proline endopeptidase-1.

Pichlo C, Juetten L, Wojtalla F, Schacherl M, Diaz D, Baumann U. Pichlo C, et al. Among authors: baumann u. J Biol Chem. 2019 Jul 26;294(30):11525-11535. doi: 10.1074/jbc.RA119.009029. Epub 2019 Jun 10. J Biol Chem. 2019. PMID: 31182482 Free PMC article.

10

Loss of GFAT-1 feedback regulation activates the hexosamine pathway that modulates protein homeostasis.

Ruegenberg S, Horn M, Pichlo C, Allmeroth K, Baumann U, Denzel MS. Ruegenberg S, et al. Among authors: baumann u. Nat Commun. 2020 Feb 4;11(1):687. doi: 10.1038/s41467-020-14524-5. Nat Commun. 2020. PMID: 32019926 Free PMC article.

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