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Intragastric Administration of Lactobacillus plantarum and 2,2'-Dithiodipyridine-Inactivated Simian Immunodeficiency Virus (SIV) Does Not Protect Indian Rhesus Macaques from Intrarectal SIV Challenge or Reduce Virus Replication after Transmission.
Carnathan DG, Mackel JJ, Sweat SL, Enemuo CA, Gebru EH, Dhadvai P, Gangadhara S, Hicks S, Vanderford TH, Amara RR, Esparza J, Lu W, Andrieu JM, Silvestri G. Carnathan DG, et al. Among authors: lu w. J Virol. 2018 Apr 27;92(10):e02030-17. doi: 10.1128/JVI.02030-17. Print 2018 May 15. J Virol. 2018. PMID: 29491157 Free PMC article.
A major obstacle to development of an effective AIDS vaccine is that along with the intended beneficial responses, the immunization regimen may activate CD4(+) T cells that can facilitate acquisition of human immunodeficiency virus (HIV) by serving as target cells for the virus. …
A major obstacle to development of an effective AIDS vaccine is that along with the intended beneficial responses, the immunization regimen …
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