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Chimeric peptide EP45 as a dual agonist at GLP-1 and NPY2R receptors.
Chepurny OG, Bonaccorso RL, Leech CA, Wöllert T, Langford GM, Schwede F, Roth CL, Doyle RP, Holz GG. Chepurny OG, et al. Among authors: bonaccorso rl. Sci Rep. 2018 Feb 28;8(1):3749. doi: 10.1038/s41598-018-22106-1. Sci Rep. 2018. PMID: 29491394 Free PMC article.
A vitamin B12 conjugate of exendin-4 improves glucose tolerance without associated nausea or hypophagia in rodents.
Mietlicki-Baase EG, Liberini CG, Workinger JL, Bonaccorso RL, Borner T, Reiner DJ, Koch-Laskowski K, McGrath LE, Lhamo R, Stein LM, De Jonghe BC, Holz GG, Roth CL, Doyle RP, Hayes MR. Mietlicki-Baase EG, et al. Among authors: bonaccorso rl. Diabetes Obes Metab. 2018 May;20(5):1223-1234. doi: 10.1111/dom.13222. Epub 2018 Feb 20. Diabetes Obes Metab. 2018. PMID: 29327400 Free PMC article.