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Workshop on acceleration of the validation and regulatory acceptance of alternative methods and implementation of testing strategies.
Piersma AH, Burgdorf T, Louekari K, Desprez B, Taalman R, Landsiedel R, Barroso J, Rogiers V, Eskes C, Oelgeschläger M, Whelan M, Braeuning A, Vinggaard AM, Kienhuis A, van Benthem J, Ezendam J. Piersma AH, et al. Among authors: ezendam j. Toxicol In Vitro. 2018 Aug;50:62-74. doi: 10.1016/j.tiv.2018.02.018. Epub 2018 Mar 2. Toxicol In Vitro. 2018. PMID: 29501630 Free article.
Transfer of a two-tiered keratinocyte assay: IL-18 production by NCTC2544 to determine the skin sensitizing capacity and epidermal equivalent assay to determine sensitizer potency.
Teunis M, Corsini E, Smits M, Madsen CB, Eltze T, Ezendam J, Galbiati V, Gremmer E, Krul C, Landin A, Landsiedel R, Pieters R, Rasmussen TF, Reinders J, Roggen E, Spiekstra S, Gibbs S. Teunis M, et al. Among authors: ezendam j. Toxicol In Vitro. 2013 Apr;27(3):1135-50. doi: 10.1016/j.tiv.2012.06.004. Epub 2012 Jun 19. Toxicol In Vitro. 2013. PMID: 22728231
Integrated Testing Strategies (ITS) for safety assessment.
Rovida C, Alépée N, Api AM, Basketter DA, Bois FY, Caloni F, Corsini E, Daneshian M, Eskes C, Ezendam J, Fuchs H, Hayden P, Hegele-Hartung C, Hoffmann S, Hubesch B, Jacobs MN, Jaworska J, Kleensang A, Kleinstreuer N, Lalko J, Landsiedel R, Lebreux F, Luechtefeld T, Locatelli M, Mehling A, Natsch A, Pitchford JW, Prater D, Prieto P, Schepky A, Schüürmann G, Smirnova L, Toole C, van Vliet E, Weisensee D, Hartung T. Rovida C, et al. Among authors: ezendam j. ALTEX. 2015;32(1):25-40. doi: 10.14573/altex.1411011. Epub 2014 Nov 19. ALTEX. 2015. PMID: 25413849 Free article.
Developing a framework for assessing chemical respiratory sensitization: A workshop report.
North CM, Ezendam J, Hotchkiss JA, Maier C, Aoyama K, Enoch S, Goetz A, Graham C, Kimber I, Karjalainen A, Pauluhn J, Roggen EL, Selgrade M, Tarlo SM, Chen CL. North CM, et al. Among authors: ezendam j. Regul Toxicol Pharmacol. 2016 Oct;80:295-309. doi: 10.1016/j.yrtph.2016.06.006. Epub 2016 Jul 7. Regul Toxicol Pharmacol. 2016. PMID: 27396307
Validation redefined.
Piersma AH, van Benthem J, Ezendam J, Kienhuis AS. Piersma AH, et al. Among authors: ezendam j. Toxicol In Vitro. 2018 Feb;46:163-165. doi: 10.1016/j.tiv.2017.10.013. Epub 2017 Oct 9. Toxicol In Vitro. 2018. PMID: 29024777 No abstract available.
66 results