Petsko GA - Search Results

1

Stabilizing the Retromer Complex in a Human Stem Cell Model of Alzheimer's Disease Reduces TAU Phosphorylation Independently of Amyloid Precursor Protein.

Young JE, Fong LK, Frankowski H, Petsko GA, Small SA, Goldstein LSB. Young JE, et al. Among authors: petsko ga. Stem Cell Reports. 2018 Mar 13;10(3):1046-1058. doi: 10.1016/j.stemcr.2018.01.031. Epub 2018 Mar 1. Stem Cell Reports. 2018. PMID: 29503090 Free PMC article.

2

Polyamine pathway contributes to the pathogenesis of Parkinson disease.

Lewandowski NM, Ju S, Verbitsky M, Ross B, Geddie ML, Rockenstein E, Adame A, Muhammad A, Vonsattel JP, Ringe D, Cote L, Lindquist S, Masliah E, Petsko GA, Marder K, Clark LN, Small SA. Lewandowski NM, et al. Among authors: petsko ga. Proc Natl Acad Sci U S A. 2010 Sep 28;107(39):16970-5. doi: 10.1073/pnas.1011751107. Epub 2010 Sep 13. Proc Natl Acad Sci U S A. 2010. PMID: 20837543 Free PMC article.

3

Pharmacological chaperones stabilize retromer to limit APP processing.

Mecozzi VJ, Berman DE, Simoes S, Vetanovetz C, Awal MR, Patel VM, Schneider RT, Petsko GA, Ringe D, Small SA. Mecozzi VJ, et al. Among authors: petsko ga. Nat Chem Biol. 2014 Jun;10(6):443-9. doi: 10.1038/nchembio.1508. Epub 2014 Apr 20. Nat Chem Biol. 2014. PMID: 24747528 Free PMC article.

4

The use of pharmacological retromer chaperones in Alzheimer's disease and other endosomal-related disorders.

Berman DE, Ringe D, Petsko GA, Small SA. Berman DE, et al. Among authors: petsko ga. Neurotherapeutics. 2015 Jan;12(1):12-8. doi: 10.1007/s13311-014-0321-y. Neurotherapeutics. 2015. PMID: 25472693 Free PMC article. Review.

5

Retromer in Alzheimer disease, Parkinson disease and other neurological disorders.

Small SA, Petsko GA. Small SA, et al. Among authors: petsko ga. Nat Rev Neurosci. 2015 Mar;16(3):126-32. doi: 10.1038/nrn3896. Epub 2015 Feb 11. Nat Rev Neurosci. 2015. PMID: 25669742 Review.

6

Endosomal Traffic Jams Represent a Pathogenic Hub and Therapeutic Target in Alzheimer's Disease.

Small SA, Simoes-Spassov S, Mayeux R, Petsko GA. Small SA, et al. Among authors: petsko ga. Trends Neurosci. 2017 Oct;40(10):592-602. doi: 10.1016/j.tins.2017.08.003. Trends Neurosci. 2017. PMID: 28962801 Free PMC article. Review.

7

Cholera toxin inhibits SNX27-retromer-mediated delivery of cargo proteins to the plasma membrane.

Singh V, Yang J, Yin J, Cole R, Tse M, Berman DE, Small SA, Petsko G, Donowitz M. Singh V, et al. J Cell Sci. 2018 Aug 17;131(16):jcs218610. doi: 10.1242/jcs.218610. J Cell Sci. 2018. PMID: 30030371 Free PMC article.

8

Endosomal recycling reconciles the Alzheimer's disease paradox.

Small SA, Petsko GA. Small SA, et al. Among authors: petsko ga. Sci Transl Med. 2020 Dec 2;12(572):eabb1717. doi: 10.1126/scitranslmed.abb1717. Sci Transl Med. 2020. PMID: 33268506 Free PMC article. Review.

9

The neuronal retromer can regulate both neuronal and microglial phenotypes of Alzheimer's disease.

Qureshi YH, Berman DE, Marsh SE, Klein RL, Patel VM, Simoes S, Kannan S, Petsko GA, Stevens B, Small SA. Qureshi YH, et al. Among authors: petsko ga. Cell Rep. 2022 Jan 18;38(3):110262. doi: 10.1016/j.celrep.2021.110262. Cell Rep. 2022. PMID: 35045281 Free PMC article.

10

Elucidating the causes of neurodegeneration.

Petsko GA, Small SA. Petsko GA, et al. Science. 2022 Jul;377(6601):31-32. doi: 10.1126/science.adc9969. Epub 2022 Jun 30. Science. 2022. PMID: 35771902

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