Martin DDO - Search Results

1

Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease.

Ehrnhoefer DE, Martin DDO, Schmidt ME, Qiu X, Ladha S, Caron NS, Skotte NH, Nguyen YTN, Vaid K, Southwell AL, Engemann S, Franciosi S, Hayden MR. Ehrnhoefer DE, et al. Among authors: martin ddo. Acta Neuropathol Commun. 2018 Mar 6;6(1):16. doi: 10.1186/s40478-018-0518-0. Acta Neuropathol Commun. 2018. PMID: 29510748 Free PMC article.

2

The Salmonella type III effector SspH2 specifically exploits the NLR co-chaperone activity of SGT1 to subvert immunity.

Bhavsar AP, Brown NF, Stoepel J, Wiermer M, Martin DD, Hsu KJ, Imami K, Ross CJ, Hayden MR, Foster LJ, Li X, Hieter P, Finlay BB. Bhavsar AP, et al. PLoS Pathog. 2013;9(7):e1003518. doi: 10.1371/journal.ppat.1003518. Epub 2013 Jul 25. PLoS Pathog. 2013. PMID: 23935490 Free PMC article.

3

Identification of a post-translationally myristoylated autophagy-inducing domain released by caspase cleavage of huntingtin.

Martin DD, Heit RJ, Yap MC, Davidson MW, Hayden MR, Berthiaume LG. Martin DD, et al. Hum Mol Genet. 2014 Jun 15;23(12):3166-79. doi: 10.1093/hmg/ddu027. Epub 2014 Jan 23. Hum Mol Genet. 2014. PMID: 24459296 Free PMC article.

4

The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease.

Butland SL, Sanders SS, Schmidt ME, Riechers SP, Lin DT, Martin DD, Vaid K, Graham RK, Singaraja RR, Wanker EE, Conibear E, Hayden MR. Butland SL, et al. Hum Mol Genet. 2014 Aug 1;23(15):4142-60. doi: 10.1093/hmg/ddu137. Epub 2014 Apr 4. Hum Mol Genet. 2014. PMID: 24705354 Free PMC article.

5

Autophagy in Huntington disease and huntingtin in autophagy.

Martin DD, Ladha S, Ehrnhoefer DE, Hayden MR. Martin DD, et al. Trends Neurosci. 2015 Jan;38(1):26-35. doi: 10.1016/j.tins.2014.09.003. Epub 2014 Oct 2. Trends Neurosci. 2015. PMID: 25282404 Review.

6

Partial rescue of some features of Huntington Disease in the genetic absence of caspase-6 in YAC128 mice.

Wong BKY, Ehrnhoefer DE, Graham RK, Martin DDO, Ladha S, Uribe V, Stanek LM, Franciosi S, Qiu X, Deng Y, Kovalik V, Zhang W, Pouladi MA, Shihabuddin LS, Hayden MR. Wong BKY, et al. Among authors: martin ddo. Neurobiol Dis. 2015 Apr;76:24-36. doi: 10.1016/j.nbd.2014.12.030. Epub 2015 Jan 9. Neurobiol Dis. 2015. PMID: 25583186

7

Post-translational myristoylation at the cross roads of cell death, autophagy and neurodegeneration.

Martin DD, Hayden MR. Martin DD, et al. Biochem Soc Trans. 2015 Apr;43(2):229-34. doi: 10.1042/BST20140281. Biochem Soc Trans. 2015. PMID: 25849922

8

Curation of the Mammalian Palmitoylome Indicates a Pivotal Role for Palmitoylation in Diseases and Disorders of the Nervous System and Cancers.

Sanders SS, Martin DD, Butland SL, Lavallée-Adam M, Calzolari D, Kay C, Yates JR 3rd, Hayden MR. Sanders SS, et al. PLoS Comput Biol. 2015 Aug 14;11(8):e1004405. doi: 10.1371/journal.pcbi.1004405. eCollection 2015 Aug. PLoS Comput Biol. 2015. PMID: 26275289 Free PMC article.

9

Neurodegeneration: Role of repeats in protein clearance.

Martin DDO, Hayden MR. Martin DDO, et al. Nature. 2017 May 4;545(7652):33-34. doi: 10.1038/nature22489. Epub 2017 Apr 26. Nature. 2017. PMID: 28445458 No abstract available.

10

A human huntingtin SNP alters post-translational modification and pathogenic proteolysis of the protein causing Huntington disease.

Martin DDO, Kay C, Collins JA, Nguyen YT, Slama RA, Hayden MR. Martin DDO, et al. Sci Rep. 2018 May 25;8(1):8096. doi: 10.1038/s41598-018-25903-w. Sci Rep. 2018. PMID: 29802276 Free PMC article.

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