Kshirsagar R - Search Results

1

Lipidomics of CHO Cell Bioprocessing: Relation to Cell Growth and Specific Productivity of a Monoclonal Antibody.

Ali AS, Raju R, Ray S, Kshirsagar R, Gilbert A, Zang L, Karger BL. Ali AS, et al. Among authors: kshirsagar r. Biotechnol J. 2018 Oct;13(10):e1700745. doi: 10.1002/biot.201700745. Epub 2018 Mar 26. Biotechnol J. 2018. PMID: 29521466

2

Multi-Omics Study on the Impact of Cysteine Feed Level on Cell Viability and mAb Production in a CHO Bioprocess.

Ali AS, Raju R, Kshirsagar R, Ivanov AR, Gilbert A, Zang L, Karger BL. Ali AS, et al. Among authors: kshirsagar r. Biotechnol J. 2019 Apr;14(4):e1800352. doi: 10.1002/biot.201800352. Epub 2018 Dec 14. Biotechnol J. 2019. PMID: 30485675

3

Multi-Omics Reveals Impact of Cysteine Feed Concentration and Resulting Redox Imbalance on Cellular Energy Metabolism and Specific Productivity in CHO Cell Bioprocessing.

Ali AS, Chen R, Raju R, Kshirsagar R, Gilbert A, Zang L, Karger BL, Ivanov AR. Ali AS, et al. Among authors: kshirsagar r. Biotechnol J. 2020 Aug;15(8):e1900565. doi: 10.1002/biot.201900565. Epub 2020 Apr 3. Biotechnol J. 2020. PMID: 32170810 Free PMC article.

4

Controlling trisulfide modification in recombinant monoclonal antibody produced in fed-batch cell culture.

Kshirsagar R, McElearney K, Gilbert A, Sinacore M, Ryll T. Kshirsagar R, et al. Biotechnol Bioeng. 2012 Oct;109(10):2523-32. doi: 10.1002/bit.24511. Epub 2012 Apr 9. Biotechnol Bioeng. 2012. PMID: 22473825

5

Investigation of metabolic variability observed in extended fed batch cell culture.

Gilbert A, McElearney K, Kshirsagar R, Sinacore MS, Ryll T. Gilbert A, et al. Among authors: kshirsagar r. Biotechnol Prog. 2013 Nov-Dec;29(6):1519-27. doi: 10.1002/btpr.1787. Epub 2013 Sep 10. Biotechnol Prog. 2013. PMID: 23926083

6

Integration of cell line and process development to overcome the challenge of a difficult to express protein.

Alves CS, Gilbert A, Dalvi S, St Germain B, Xie W, Estes S, Kshirsagar R, Ryll T. Alves CS, et al. Among authors: kshirsagar r. Biotechnol Prog. 2015 Sep-Oct;31(5):1201-11. doi: 10.1002/btpr.2091. Epub 2015 May 11. Biotechnol Prog. 2015. PMID: 25919541

7

Tryptophan oxidation catabolite, N-formylkynurenine, in photo degraded cell culture medium results in reduced cell culture performance.

McElearney K, Ali A, Gilbert A, Kshirsagar R, Zang L. McElearney K, et al. Among authors: kshirsagar r. Biotechnol Prog. 2016 Jan-Feb;32(1):74-82. doi: 10.1002/btpr.2198. Epub 2015 Dec 1. Biotechnol Prog. 2016. PMID: 26560839

8

Using Metabolomics to Identify Cell Line-Independent Indicators of Growth Inhibition for Chinese Hamster Ovary Cell-based Bioprocesses.

Alden N, Raju R, McElearney K, Lambropoulos J, Kshirsagar R, Gilbert A, Lee K. Alden N, et al. Among authors: kshirsagar r. Metabolites. 2020 May 15;10(5):199. doi: 10.3390/metabo10050199. Metabolites. 2020. PMID: 32429145 Free PMC article.

9

Analysis of dynamic changes in the proteome of a Bcl-XL overexpressing Chinese hamster ovary cell culture during exponential and stationary phases.

Carlage T, Kshirsagar R, Zang L, Janakiraman V, Hincapie M, Lyubarskaya Y, Weiskopf A, Hancock WS. Carlage T, et al. Among authors: kshirsagar r. Biotechnol Prog. 2012 May-Jun;28(3):814-23. doi: 10.1002/btpr.1534. Epub 2012 May 2. Biotechnol Prog. 2012. PMID: 22556165

10

Addition of valproic acid to CHO cell fed-batch cultures improves monoclonal antibody titers.

Yang WC, Lu J, Nguyen NB, Zhang A, Healy NV, Kshirsagar R, Ryll T, Huang YM. Yang WC, et al. Among authors: kshirsagar r. Mol Biotechnol. 2014 May;56(5):421-8. doi: 10.1007/s12033-013-9725-x. Mol Biotechnol. 2014. PMID: 24381145

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