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SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis.
Ikeda F, Deribe YL, Skånland SS, Stieglitz B, Grabbe C, Franz-Wachtel M, van Wijk SJ, Goswami P, Nagy V, Terzic J, Tokunaga F, Androulidaki A, Nakagawa T, Pasparakis M, Iwai K, Sundberg JP, Schaefer L, Rittinger K, Macek B, Dikic I. Ikeda F, et al. Among authors: pasparakis m. Nature. 2011 Mar 31;471(7340):637-41. doi: 10.1038/nature09814. Nature. 2011. PMID: 21455181 Free PMC article.
Improved HSC reconstitution and protection from inflammatory stress and chemotherapy in mice lacking granzyme B.
Carnevalli LS, Scognamiglio R, Cabezas-Wallscheid N, Rahmig S, Laurenti E, Masuda K, Jöckel L, Kuck A, Sujer S, Polykratis A, Erlacher M, Pasparakis M, Essers MA, Trumpp A. Carnevalli LS, et al. Among authors: pasparakis m. J Exp Med. 2014 May 5;211(5):769-79. doi: 10.1084/jem.20131072. Epub 2014 Apr 21. J Exp Med. 2014. PMID: 24752302 Free PMC article.
RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis.
Dannappel M, Vlantis K, Kumari S, Polykratis A, Kim C, Wachsmuth L, Eftychi C, Lin J, Corona T, Hermance N, Zelic M, Kirsch P, Basic M, Bleich A, Kelliher M, Pasparakis M. Dannappel M, et al. Among authors: pasparakis m. Nature. 2014 Sep 4;513(7516):90-4. doi: 10.1038/nature13608. Epub 2014 Aug 17. Nature. 2014. PMID: 25132550 Free PMC article.
IRF5:RelA interaction targets inflammatory genes in macrophages.
Saliba DG, Heger A, Eames HL, Oikonomopoulos S, Teixeira A, Blazek K, Androulidaki A, Wong D, Goh FG, Weiss M, Byrne A, Pasparakis M, Ragoussis J, Udalova IA. Saliba DG, et al. Among authors: pasparakis m. Cell Rep. 2014 Sep 11;8(5):1308-17. doi: 10.1016/j.celrep.2014.07.034. Epub 2014 Aug 21. Cell Rep. 2014. PMID: 25159141 Free PMC article.
202 results