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Integration of ζ-deficient CARs into the CD3-zeta gene conveys potent cytotoxicity in T and NK cells.
Kath J, Franke C, Drosdek V, Du W, Glaser V, Fuster-Garcia C, Stein M, Zittel T, Schulenberg S, Porter CE, Andersch L, Künkele A, Alcaniz J, Hoffmann J, Abken H, Abou-El-Enein M, Pruß A, Suzuki M, Cathomen T, Stripecke R, Volk HD, Reinke P, Schmueck-Henneresse M, Wagner DL. Kath J, et al. Among authors: cathomen t. bioRxiv [Preprint]. 2023 Nov 14:2023.11.10.565518. doi: 10.1101/2023.11.10.565518. bioRxiv. 2023. Update in: Blood. 2024 Jun 20;143(25):2599-2611. doi: 10.1182/blood.2023020973 PMID: 38116030 Free PMC article. Updated. Preprint.
MicroRNA-221 regulates FAS-induced fulminant liver failure.
Sharma AD, Narain N, Händel EM, Iken M, Singhal N, Cathomen T, Manns MP, Schöler HR, Ott M, Cantz T. Sharma AD, et al. Among authors: cathomen t. Hepatology. 2011 May;53(5):1651-61. doi: 10.1002/hep.24243. Epub 2011 Mar 11. Hepatology. 2011. PMID: 21400558
Efficient designer nuclease-based homologous recombination enables direct PCR screening for footprintless targeted human pluripotent stem cells.
Merkert S, Wunderlich S, Bednarski C, Beier J, Haase A, Dreyer AK, Schwanke K, Meyer J, Göhring G, Cathomen T, Martin U. Merkert S, et al. Among authors: cathomen t. Stem Cell Reports. 2014 Jan 14;2(1):107-18. doi: 10.1016/j.stemcr.2013.12.003. eCollection 2014 Jan 14. Stem Cell Reports. 2014. PMID: 24678453 Free PMC article.
Modeling MyD88 Deficiency In Vitro Provides New Insights in Its Function.
Craig-Mueller N, Hammad R, Elling R, Alzubi J, Timm B, Kolter J, Knelangen N, Bednarski C, Gläser B, Ammann S, Ivics Z, Fischer J, Speckmann C, Schwarz K, Lachmann N, Ehl S, Moritz T, Henneke P, Cathomen T. Craig-Mueller N, et al. Among authors: cathomen t. Front Immunol. 2020 Dec 23;11:608802. doi: 10.3389/fimmu.2020.608802. eCollection 2020. Front Immunol. 2020. PMID: 33424861 Free PMC article.
Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations.
Schubert D, Bode C, Kenefeck R, Hou TZ, Wing JB, Kennedy A, Bulashevska A, Petersen BS, Schäffer AA, Grüning BA, Unger S, Frede N, Baumann U, Witte T, Schmidt RE, Dueckers G, Niehues T, Seneviratne S, Kanariou M, Speckmann C, Ehl S, Rensing-Ehl A, Warnatz K, Rakhmanov M, Thimme R, Hasselblatt P, Emmerich F, Cathomen T, Backofen R, Fisch P, Seidl M, May A, Schmitt-Graeff A, Ikemizu S, Salzer U, Franke A, Sakaguchi S, Walker LSK, Sansom DM, Grimbacher B. Schubert D, et al. Among authors: cathomen t. Nat Med. 2014 Dec;20(12):1410-1416. doi: 10.1038/nm.3746. Epub 2014 Oct 20. Nat Med. 2014. PMID: 25329329 Free PMC article.
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