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Atrx inactivation drives disease-defining phenotypes in glioma cells of origin through global epigenomic remodeling.
Danussi C, Bose P, Parthasarathy PT, Silberman PC, Van Arnam JS, Vitucci M, Tang OY, Heguy A, Wang Y, Chan TA, Riggins GJ, Sulman EP, Lang FF, Creighton CJ, Deneen B, Miller CR, Picketts DJ, Kannan K, Huse JT. Danussi C, et al. Among authors: lang ff. Nat Commun. 2018 Mar 13;9(1):1057. doi: 10.1038/s41467-018-03476-6. Nat Commun. 2018. PMID: 29535300 Free PMC article.
The transcriptional coactivator TAZ regulates mesenchymal differentiation in malignant glioma.
Bhat KP, Salazar KL, Balasubramaniyan V, Wani K, Heathcock L, Hollingsworth F, James JD, Gumin J, Diefes KL, Kim SH, Turski A, Azodi Y, Yang Y, Doucette T, Colman H, Sulman EP, Lang FF, Rao G, Copray S, Vaillant BD, Aldape KD. Bhat KP, et al. Among authors: lang ff. Genes Dev. 2011 Dec 15;25(24):2594-609. doi: 10.1101/gad.176800.111. Genes Dev. 2011. PMID: 22190458 Free PMC article.
Novel HSP90 inhibitor NVP-HSP990 targets cell-cycle regulators to ablate Olig2-positive glioma tumor-initiating cells.
Fu J, Koul D, Yao J, Wang S, Yuan Y, Colman H, Sulman EP, Lang FF, Yung WK. Fu J, et al. Among authors: lang ff. Cancer Res. 2013 May 15;73(10):3062-74. doi: 10.1158/0008-5472.CAN-12-2033. Epub 2013 Mar 14. Cancer Res. 2013. Retraction in: Cancer Res. 2014 Nov 15;74(22):6731-2. doi: 10.1158/0008-5472.CAN-14-2966 PMID: 23492364 Free PMC article. Retracted.
Integrated chromosome 19 transcriptomic and proteomic data sets derived from glioma cancer stem-cell lines.
Lichti CF, Liu H, Shavkunov AS, Mostovenko E, Sulman EP, Ezhilarasan R, Wang Q, Kroes RA, Moskal JC, Fenyö D, Oksuz BA, Conrad CA, Lang FF, Berven FS, Végvári A, Rezeli M, Marko-Varga G, Hober S, Nilsson CL. Lichti CF, et al. Among authors: lang ff. J Proteome Res. 2014 Jan 3;13(1):191-9. doi: 10.1021/pr400786s. Epub 2013 Dec 3. J Proteome Res. 2014. PMID: 24266786
Mesenchymal Stem Cells Isolated From Human Gliomas Increase Proliferation and Maintain Stemness of Glioma Stem Cells Through the IL-6/gp130/STAT3 Pathway.
Hossain A, Gumin J, Gao F, Figueroa J, Shinojima N, Takezaki T, Priebe W, Villarreal D, Kang SG, Joyce C, Sulman E, Wang Q, Marini FC, Andreeff M, Colman H, Lang FF. Hossain A, et al. Among authors: lang ff. Stem Cells. 2015 Aug;33(8):2400-15. doi: 10.1002/stem.2053. Epub 2015 May 27. Stem Cells. 2015. PMID: 25966666 Free PMC article.
Suppression of RAF/MEK or PI3K synergizes cytotoxicity of receptor tyrosine kinase inhibitors in glioma tumor-initiating cells.
Shingu T, Holmes L, Henry V, Wang Q, Latha K, Gururaj AE, Gibson LA, Doucette T, Lang FF, Rao G, Yuan L, Sulman EP, Farrell NP, Priebe W, Hess KR, Wang YA, Hu J, Bögler O. Shingu T, et al. Among authors: lang ff. J Transl Med. 2016 Feb 9;14:46. doi: 10.1186/s12967-016-0803-2. J Transl Med. 2016. PMID: 26861698 Free PMC article.
265 results