Brown MP - Search Results

1

Logic-gated approaches to extend the utility of chimeric antigen receptor T-cell technology.

Ebert LM, Yu W, Gargett T, Brown MP. Ebert LM, et al. Among authors: brown mp. Biochem Soc Trans. 2018 Apr 17;46(2):391-401. doi: 10.1042/BST20170178. Epub 2018 Mar 14. Biochem Soc Trans. 2018. PMID: 29540509 Review.

2

The inducible caspase-9 suicide gene system as a "safety switch" to limit on-target, off-tumor toxicities of chimeric antigen receptor T cells.

Gargett T, Brown MP. Gargett T, et al. Among authors: brown mp. Front Pharmacol. 2014 Oct 28;5:235. doi: 10.3389/fphar.2014.00235. eCollection 2014. Front Pharmacol. 2014. PMID: 25389405 Free PMC article. Review.

3

BRAF and MEK inhibition variably affect GD2-specific chimeric antigen receptor (CAR) T-cell function in vitro.

Gargett T, Fraser CK, Dotti G, Yvon ES, Brown MP. Gargett T, et al. Among authors: brown mp. J Immunother. 2015 Jan;38(1):12-23. doi: 10.1097/CJI.0000000000000061. J Immunother. 2015. PMID: 25415284

4

Different cytokine and stimulation conditions influence the expansion and immune phenotype of third-generation chimeric antigen receptor T cells specific for tumor antigen GD2.

Gargett T, Brown MP. Gargett T, et al. Among authors: brown mp. Cytotherapy. 2015 Apr;17(4):487-95. doi: 10.1016/j.jcyt.2014.12.002. Epub 2015 Jan 6. Cytotherapy. 2015. PMID: 25573334

5

GD2-specific CAR T Cells Undergo Potent Activation and Deletion Following Antigen Encounter but can be Protected From Activation-induced Cell Death by PD-1 Blockade.

Gargett T, Yu W, Dotti G, Yvon ES, Christo SN, Hayball JD, Lewis ID, Brenner MK, Brown MP. Gargett T, et al. Among authors: brown mp. Mol Ther. 2016 Jun;24(6):1135-1149. doi: 10.1038/mt.2016.63. Epub 2016 Mar 29. Mol Ther. 2016. PMID: 27019998 Free PMC article. Clinical Trial.

6

Desmoglein 2 promotes vasculogenic mimicry in melanoma and is associated with poor clinical outcome.

Tan LY, Mintoff C, Johan MZ, Ebert BW, Fedele C, Zhang YF, Szeto P, Sheppard KE, McArthur GA, Foster-Smith E, Ruszkiewicz A, Brown MP, Bonder CS, Shackleton M, Ebert LM. Tan LY, et al. Among authors: brown mp. Oncotarget. 2016 Jul 19;7(29):46492-46508. doi: 10.18632/oncotarget.10216. Oncotarget. 2016. PMID: 27340778 Free PMC article.

7

GM-CSF signalling blockade and chemotherapeutic agents act in concert to inhibit the function of myeloid-derived suppressor cells in vitro.

Gargett T, Christo SN, Hercus TR, Abbas N, Singhal N, Lopez AF, Brown MP. Gargett T, et al. Among authors: brown mp. Clin Transl Immunology. 2016 Dec 23;5(12):e119. doi: 10.1038/cti.2016.80. eCollection 2016 Dec. Clin Transl Immunology. 2016. PMID: 28090321 Free PMC article.

8

Comment on "KB004, a first in class monoclonal antibody targeting the receptor tyrosine kinase EphA3, in patients with advanced hematologic malignancies: Results from a phase 1 study".

Hughes A, Clarson J, Gargett T, Yu W, Brown MP, Lopez AF, Hughes TP, Yong AS. Hughes A, et al. Among authors: brown mp. Leuk Res. 2017 Apr;55:55-57. doi: 10.1016/j.leukres.2017.01.009. Epub 2017 Jan 9. Leuk Res. 2017. PMID: 28129558 No abstract available.

9

Control of immune cell entry through the tumour vasculature: a missing link in optimising melanoma immunotherapy?

Tan LY, Martini C, Fridlender ZG, Bonder CS, Brown MP, Ebert LM. Tan LY, et al. Among authors: brown mp. Clin Transl Immunology. 2017 Mar 17;6(3):e134. doi: 10.1038/cti.2017.7. eCollection 2017 Mar. Clin Transl Immunology. 2017. PMID: 28435677 Free PMC article. Review.

10

Phase I trial of Lipovaxin-MM, a novel dendritic cell-targeted liposomal vaccine for malignant melanoma.

Gargett T, Abbas MN, Rolan P, Price JD, Gosling KM, Ferrante A, Ruszkiewicz A, Atmosukarto IIC, Altin J, Parish CR, Brown MP. Gargett T, et al. Among authors: brown mp. Cancer Immunol Immunother. 2018 Sep;67(9):1461-1472. doi: 10.1007/s00262-018-2207-z. Epub 2018 Jul 16. Cancer Immunol Immunother. 2018. PMID: 30014244 Free PMC article. Clinical Trial.

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