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Page 1
Early childhood gut microbiomes show strong geographic differences among subjects at high risk for type 1 diabetes.
Kemppainen KM, Ardissone AN, Davis-Richardson AG, Fagen JR, Gano KA, León-Novelo LG, Vehik K, Casella G, Simell O, Ziegler AG, Rewers MJ, Lernmark Å, Hagopian W, She JX, Krischer JP, Akolkar B, Schatz DA, Atkinson MA, Triplett EW; TEDDY Study Group. Kemppainen KM, et al. Among authors: triplett ew. Diabetes Care. 2015 Feb;38(2):329-32. doi: 10.2337/dc14-0850. Epub 2014 Dec 17. Diabetes Care. 2015. PMID: 25519450 Free PMC article.
Factors That Increase Risk of Celiac Disease Autoimmunity After a Gastrointestinal Infection in Early Life.
Kemppainen KM, Lynch KF, Liu E, Lönnrot M, Simell V, Briese T, Koletzko S, Hagopian W, Rewers M, She JX, Simell O, Toppari J, Ziegler AG, Akolkar B, Krischer JP, Lernmark Å, Hyöty H, Triplett EW, Agardh D; TEDDY Study Group. Kemppainen KM, et al. Among authors: triplett ew. Clin Gastroenterol Hepatol. 2017 May;15(5):694-702.e5. doi: 10.1016/j.cgh.2016.10.033. Epub 2016 Nov 10. Clin Gastroenterol Hepatol. 2017. PMID: 27840181 Free PMC article.
Association Between Early-Life Antibiotic Use and the Risk of Islet or Celiac Disease Autoimmunity.
Kemppainen KM, Vehik K, Lynch KF, Larsson HE, Canepa RJ, Simell V, Koletzko S, Liu E, Simell OG, Toppari J, Ziegler AG, Rewers MJ, Lernmark Å, Hagopian WA, She JX, Akolkar B, Schatz DA, Atkinson MA, Blaser MJ, Krischer JP, Hyöty H, Agardh D, Triplett EW; Environmental Determinants of Diabetes in the Young (TEDDY) Study Group. Kemppainen KM, et al. Among authors: triplett ew. JAMA Pediatr. 2017 Dec 1;171(12):1217-1225. doi: 10.1001/jamapediatrics.2017.2905. JAMA Pediatr. 2017. PMID: 29052687 Free PMC article.
Telomere length is not a main factor for the development of islet autoimmunity and type 1 diabetes in the TEDDY study.
Törn C, Liu X, Onengut-Gumuscu S, Counts KM, Moreno JL, Remedios CL, Chen WM, LeFaive J, Butterworth MD, Akolkar B, Krischer JP, Lernmark Å, Rewers M, She JX, Toppari J, Ziegler AG, Ratan A, Smith AV, Hagopian WA, Rich SS, Parikh HM; TEDDY Study Group. Törn C, et al. Sci Rep. 2022 Mar 16;12(1):4516. doi: 10.1038/s41598-022-08058-7. Sci Rep. 2022. PMID: 35296692 Free PMC article.
Temporal changes in gastrointestinal fungi and the risk of autoimmunity during early childhood: the TEDDY study.
Auchtung TA, Stewart CJ, Smith DP, Triplett EW, Agardh D, Hagopian WA, Ziegler AG, Rewers MJ, She JX, Toppari J, Lernmark Å, Akolkar B, Krischer JP, Vehik K, Auchtung JM, Ajami NJ, Petrosino JF. Auchtung TA, et al. Among authors: triplett ew. Nat Commun. 2022 Jun 7;13(1):3151. doi: 10.1038/s41467-022-30686-w. Nat Commun. 2022. PMID: 35672407 Free PMC article.
Gut microbiome markers in subgroups of HLA class II genotyped infants signal future celiac disease in the general population: ABIS study.
Milletich PL, Ahrens AP, Russell JT, Petrone JR, Berryman MA, Agardh D, Ludvigsson JF, Triplett EW, Ludvigsson J. Milletich PL, et al. Among authors: triplett ew. Front Cell Infect Microbiol. 2022 Jul 25;12:920735. doi: 10.3389/fcimb.2022.920735. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 35959362 Free PMC article.
Looking back at the TEDDY study: lessons and future directions.
Lernmark Å, Agardh D, Akolkar B, Gesualdo P, Hagopian WA, Haller MJ, Hyöty H, Johnson SB, Elding Larsson H, Liu E, Lynch KF, McKinney EF, McIndoe R, Melin J, Norris JM, Rewers M, Rich SS, Toppari J, Triplett E, Vehik K, Virtanen SM, Ziegler AG, Schatz DA, Krischer J. Lernmark Å, et al. Nat Rev Endocrinol. 2024 Nov 4. doi: 10.1038/s41574-024-01045-0. Online ahead of print. Nat Rev Endocrinol. 2024. PMID: 39496810 Review.
166 results