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Monoclonal antibody targeting the β-barrel assembly machine of Escherichia coli is bactericidal.
Storek KM, Auerbach MR, Shi H, Garcia NK, Sun D, Nickerson NN, Vij R, Lin Z, Chiang N, Schneider K, Wecksler AT, Skippington E, Nakamura G, Seshasayee D, Koerber JT, Payandeh J, Smith PA, Rutherford ST. Storek KM, et al. Among authors: nickerson nn. Proc Natl Acad Sci U S A. 2018 Apr 3;115(14):3692-3697. doi: 10.1073/pnas.1800043115. Epub 2018 Mar 19. Proc Natl Acad Sci U S A. 2018. PMID: 29555747 Free PMC article.
Structure of the essential inner membrane lipopolysaccharide-PbgA complex.
Clairfeuille T, Buchholz KR, Li Q, Verschueren E, Liu P, Sangaraju D, Park S, Noland CL, Storek KM, Nickerson NN, Martin L, Dela Vega T, Miu A, Reeder J, Ruiz-Gonzalez M, Swem D, Han G, DePonte DP, Hunter MS, Gati C, Shahidi-Latham S, Xu M, Skelton N, Sellers BD, Skippington E, Sandoval W, Hanan EJ, Payandeh J, Rutherford ST. Clairfeuille T, et al. Among authors: nickerson nn. Nature. 2020 Aug;584(7821):479-483. doi: 10.1038/s41586-020-2597-x. Epub 2020 Aug 12. Nature. 2020. PMID: 32788728
Inhibition of Escherichia coli Lipoprotein Diacylglyceryl Transferase Is Insensitive to Resistance Caused by Deletion of Braun's Lipoprotein.
Diao J, Komura R, Sano T, Pantua H, Storek KM, Inaba H, Ogawa H, Noland CL, Peng Y, Gloor SL, Yan D, Kang J, Katakam AK, Volny M, Liu P, Nickerson NN, Sandoval W, Austin CD, Murray J, Rutherford ST, Reichelt M, Xu Y, Xu M, Yanagida H, Nishikawa J, Reid PC, Cunningham CN, Kapadia SB. Diao J, et al. Among authors: nickerson nn. J Bacteriol. 2021 Jun 8;203(13):e0014921. doi: 10.1128/JB.00149-21. Epub 2021 Jun 8. J Bacteriol. 2021. PMID: 33875545 Free PMC article.
Disrupting Gram-Negative Bacterial Outer Membrane Biosynthesis through Inhibition of the Lipopolysaccharide Transporter MsbA.
Alexander MK, Miu A, Oh A, Reichelt M, Ho H, Chalouni C, Labadie S, Wang L, Liang J, Nickerson NN, Hu H, Yu L, Du M, Yan D, Park S, Kim J, Xu M, Sellers BD, Purkey HE, Skelton NJ, Koehler MFT, Payandeh J, Verma V, Xu Y, Koth CM, Nishiyama M. Alexander MK, et al. Among authors: nickerson nn. Antimicrob Agents Chemother. 2018 Oct 24;62(11):e01142-18. doi: 10.1128/AAC.01142-18. Print 2018 Nov. Antimicrob Agents Chemother. 2018. PMID: 30104274 Free PMC article.
Peptidoglycan Association of Murein Lipoprotein Is Required for KpsD-Dependent Group 2 Capsular Polysaccharide Expression and Serum Resistance in a Uropathogenic Escherichia coli Isolate.
Diao J, Bouwman C, Yan D, Kang J, Katakam AK, Liu P, Pantua H, Abbas AR, Nickerson NN, Austin C, Reichelt M, Sandoval W, Xu M, Whitfield C, Kapadia SB. Diao J, et al. Among authors: nickerson nn. mBio. 2017 May 23;8(3):e00603-17. doi: 10.1128/mBio.00603-17. mBio. 2017. PMID: 28536290 Free PMC article.
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