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Page 1
Autoinhibitory regulation of S100A8/S100A9 alarmin activity locally restricts sterile inflammation.
Vogl T, Stratis A, Wixler V, Völler T, Thurainayagam S, Jorch SK, Zenker S, Dreiling A, Chakraborty D, Fröhling M, Paruzel P, Wehmeyer C, Hermann S, Papantonopoulou O, Geyer C, Loser K, Schäfers M, Ludwig S, Stoll M, Leanderson T, Schultze JL, König S, Pap T, Roth J. Vogl T, et al. Among authors: schultze jl. J Clin Invest. 2018 May 1;128(5):1852-1866. doi: 10.1172/JCI89867. Epub 2018 Apr 3. J Clin Invest. 2018. PMID: 29611822 Free PMC article.
Keratin 1 maintains skin integrity and participates in an inflammatory network in skin through interleukin-18.
Roth W, Kumar V, Beer HD, Richter M, Wohlenberg C, Reuter U, Thiering S, Staratschek-Jox A, Hofmann A, Kreusch F, Schultze JL, Vogl T, Roth J, Reichelt J, Hausser I, Magin TM. Roth W, et al. Among authors: schultze jl. J Cell Sci. 2012 Nov 15;125(Pt 22):5269-79. doi: 10.1242/jcs.116574. Epub 2012 Nov 6. J Cell Sci. 2012. PMID: 23132931 Free article.
Alarmins MRP8 and MRP14 induce stress tolerance in phagocytes under sterile inflammatory conditions.
Austermann J, Friesenhagen J, Fassl SK, Petersen B, Ortkras T, Burgmann J, Barczyk-Kahlert K, Faist E, Zedler S, Pirr S, Rohde C, Müller-Tidow C, von Köckritz-Blickwede M, von Kaisenberg CS, Flohé SB, Ulas T, Schultze JL, Roth J, Vogl T, Viemann D. Austermann J, et al. Among authors: schultze jl. Cell Rep. 2014 Dec 24;9(6):2112-23. doi: 10.1016/j.celrep.2014.11.020. Epub 2014 Dec 11. Cell Rep. 2014. PMID: 25497086 Free article.
Transcriptome assessment reveals a dominant role for TLR4 in the activation of human monocytes by the alarmin MRP8.
Fassl SK, Austermann J, Papantonopoulou O, Riemenschneider M, Xue J, Bertheloot D, Freise N, Spiekermann C, Witten A, Viemann D, Kirschnek S, Stoll M, Latz E, Schultze JL, Roth J, Vogl T. Fassl SK, et al. Among authors: schultze jl. J Immunol. 2015 Jan 15;194(2):575-83. doi: 10.4049/jimmunol.1401085. Epub 2014 Dec 10. J Immunol. 2015. PMID: 25505274 Clinical Trial.
S100-alarmin-induced innate immune programming protects newborn infants from sepsis.
Ulas T, Pirr S, Fehlhaber B, Bickes MS, Loof TG, Vogl T, Mellinger L, Heinemann AS, Burgmann J, Schöning J, Schreek S, Pfeifer S, Reuner F, Völlger L, Stanulla M, von Köckritz-Blickwede M, Glander S, Barczyk-Kahlert K, von Kaisenberg CS, Friesenhagen J, Fischer-Riepe L, Zenker S, Schultze JL, Roth J, Viemann D. Ulas T, et al. Among authors: schultze jl. Nat Immunol. 2017 Jun;18(6):622-632. doi: 10.1038/ni.3745. Epub 2017 May 1. Nat Immunol. 2017. PMID: 28459433
CD163 expression defines specific, IRF8-dependent, immune-modulatory macrophages in the bone marrow.
Fischer-Riepe L, Daber N, Schulte-Schrepping J, Véras De Carvalho BC, Russo A, Pohlen M, Fischer J, Chasan AI, Wolf M, Ulas T, Glander S, Schulz C, Skryabin B, Wollbrink Dipl-Ing A, Steingraeber N, Stremmel C, Koehle M, Gärtner F, Vettorazzi S, Holzinger D, Gross J, Rosenbauer F, Stoll M, Niemann S, Tuckermann J, Schultze JL, Roth J, Barczyk-Kahlert K. Fischer-Riepe L, et al. Among authors: schultze jl. J Allergy Clin Immunol. 2020 Nov;146(5):1137-1151. doi: 10.1016/j.jaci.2020.02.034. Epub 2020 Mar 19. J Allergy Clin Immunol. 2020. PMID: 32199911
S100A8 and S100A9 Are Important for Postnatal Development of Gut Microbiota and Immune System in Mice and Infants.
Willers M, Ulas T, Völlger L, Vogl T, Heinemann AS, Pirr S, Pagel J, Fehlhaber B, Halle O, Schöning J, Schreek S, Löber U, Essex M, Hombach P, Graspeuntner S, Basic M, Bleich A, Cloppenborg-Schmidt K, Künzel S, Jonigk D, Rupp J, Hansen G, Förster R, Baines JF, Härtel C, Schultze JL, Forslund SK, Roth J, Viemann D. Willers M, et al. Among authors: schultze jl. Gastroenterology. 2020 Dec;159(6):2130-2145.e5. doi: 10.1053/j.gastro.2020.08.019. Epub 2020 Aug 15. Gastroenterology. 2020. PMID: 32805279 Free article.
Indoleamine 2,3-dioxygenase-expressing dendritic cells form suppurative granulomas following Listeria monocytogenes infection.
Popov A, Abdullah Z, Wickenhauser C, Saric T, Driesen J, Hanisch FG, Domann E, Raven EL, Dehus O, Hermann C, Eggle D, Debey S, Chakraborty T, Krönke M, Utermöhlen O, Schultze JL. Popov A, et al. Among authors: schultze jl. J Clin Invest. 2006 Dec;116(12):3160-70. doi: 10.1172/JCI28996. Epub 2006 Nov 16. J Clin Invest. 2006. PMID: 17111046 Free PMC article.
338 results