James DJ - Search Results

1

Small molecules that inhibit the late stage of Munc13-4-dependent secretory granule exocytosis in mast cells.

Bruinsma S, James DJ, Quintana Serrano M, Esquibel J, Woo SS, Kielar-Grevstad E, Crummy E, Qurashi R, Kowalchyk JA, Martin TFJ. Bruinsma S, et al. Among authors: james dj. J Biol Chem. 2018 May 25;293(21):8217-8229. doi: 10.1074/jbc.RA117.001547. Epub 2018 Apr 3. J Biol Chem. 2018. PMID: 29615494 Free PMC article.

2

Novel interactions of CAPS (Ca2+-dependent activator protein for secretion) with the three neuronal SNARE proteins required for vesicle fusion.

Daily NJ, Boswell KL, James DJ, Martin TF. Daily NJ, et al. Among authors: james dj. J Biol Chem. 2010 Nov 12;285(46):35320-9. doi: 10.1074/jbc.M110.145169. Epub 2010 Sep 8. J Biol Chem. 2010. PMID: 20826818 Free PMC article.

3

Munc13-4 reconstitutes calcium-dependent SNARE-mediated membrane fusion.

Boswell KL, James DJ, Esquibel JM, Bruinsma S, Shirakawa R, Horiuchi H, Martin TF. Boswell KL, et al. Among authors: james dj. J Cell Biol. 2012 Apr 16;197(2):301-12. doi: 10.1083/jcb.201109132. J Cell Biol. 2012. PMID: 22508512 Free PMC article.

4

Munc13-4 functions as a Ca²⁺ sensor for homotypic secretory granule fusion to generate endosomal exocytic vacuoles.

Woo SS, James DJ, Martin TF. Woo SS, et al. Among authors: james dj. Mol Biol Cell. 2017 Mar 15;28(6):792-808. doi: 10.1091/mbc.E16-08-0617. Epub 2017 Jan 18. Mol Biol Cell. 2017. PMID: 28100639 Free PMC article.

5

Phosphatidylinositol 4,5-bisphosphate regulates SNARE-dependent membrane fusion.

James DJ, Khodthong C, Kowalchyk JA, Martin TF. James DJ, et al. J Cell Biol. 2008 Jul 28;182(2):355-66. doi: 10.1083/jcb.200801056. Epub 2008 Jul 21. J Cell Biol. 2008. PMID: 18644890 Free PMC article.

6

Munc13 homology domain-1 in CAPS/UNC31 mediates SNARE binding required for priming vesicle exocytosis.

Khodthong C, Kabachinski G, James DJ, Martin TF. Khodthong C, et al. Among authors: james dj. Cell Metab. 2011 Aug 3;14(2):254-63. doi: 10.1016/j.cmet.2011.07.002. Cell Metab. 2011. PMID: 21803295 Free PMC article.

7

PRIP (phospholipase C-related but catalytically inactive protein) inhibits exocytosis by direct interactions with syntaxin 1 and SNAP-25 through its C2 domain.

Zhang Z, Takeuchi H, Gao J, Wang D, James DJ, Martin TFJ, Hirata M. Zhang Z, et al. Among authors: james dj. J Biol Chem. 2013 Mar 15;288(11):7769-7780. doi: 10.1074/jbc.M112.419317. Epub 2013 Jan 22. J Biol Chem. 2013. PMID: 23341457 Free PMC article.

8

CAPS and Munc13: CATCHRs that SNARE Vesicles.

James DJ, Martin TF. James DJ, et al. Front Endocrinol (Lausanne). 2013 Dec 4;4:187. doi: 10.3389/fendo.2013.00187. Front Endocrinol (Lausanne). 2013. PMID: 24363652 Free PMC article. Review.

9

Resident CAPS on dense-core vesicles docks and primes vesicles for fusion.

Kabachinski G, Kielar-Grevstad DM, Zhang X, James DJ, Martin TF. Kabachinski G, et al. Among authors: james dj. Mol Biol Cell. 2016 Feb 15;27(4):654-68. doi: 10.1091/mbc.E15-07-0509. Epub 2015 Dec 23. Mol Biol Cell. 2016. PMID: 26700319 Free PMC article.

10

CAPS drives trans-SNARE complex formation and membrane fusion through syntaxin interactions.

James DJ, Kowalchyk J, Daily N, Petrie M, Martin TF. James DJ, et al. Proc Natl Acad Sci U S A. 2009 Oct 13;106(41):17308-13. doi: 10.1073/pnas.0900755106. Epub 2009 Sep 29. Proc Natl Acad Sci U S A. 2009. PMID: 19805029 Free PMC article.

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